A One-Pot Palladium-Catalyzed Allylic Alkylation and Wittig Reaction of Phosphorus Ylides

被引：30

作者：

Liu, Wen-Bo ^{[1
]}

He, Hu ^{[1
]}

Dai, Li-Xin ^{[1
]}

You, Shu-Li ^{[1
]}

机构：

[1] Chinese Acad Sci, Shanghai Inst Organ Chem, State Key Lab Organometall Chem, Shanghai 200032, Peoples R China

来源：

CHEMISTRY-A EUROPEAN JOURNAL | 2010年 / 16卷 / 25期

关键词：

allenes; alkylation; allylic compounds; one-pot reactions; palladium; ylides; NEGISHI CROSS-COUPLINGS; ENANTIOSELECTIVE SYNTHESIS; ALLENIC ESTERS; OLEFINATION; COMPLEXES; HALIDES; KETENES; ROUTE;

D O I：

10.1002/chem.201000316

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

(Chemical equation presented) Put a(n) (y)lid(e) on it! The one-pot palladium-catalyzed allylic alkylation and Wittig reaction of phosphorus ylides with various aldehydes and ketenes has been realized, which produce skipped dienes, including trisubstituted alkenes and tetrasubstituted allenes, respectively (see scheme), in moderate to good overall yields. © 2010 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

引用

页码：7376 / 7379

页数：4

共 43 条

[1] REACTIONS OF CONJUGATED NITRO OLEFINS WITH PHOSPHORANES AND WITH DIMETHYLSULFOXONIUM METHYLIDE TO GIVE YLIDES AND NITROCYCLOPROPANES RESPECTIVELY [J].