Evaluation of all Types of Metabolic Bariatric Surgery and its Consequences: a Systematic Review and Meta-Analysis

被引：39
作者：
Khosravi-Largani, Matin [1 ]
Nojomi, Marzieh [2 ]
Aghili, Rokhsareh [3 ]
Otaghvar, Hamidreza Alizadeh [4 ]
Tanha, Kiarash [5 ]
Seyedi, Seyyed Hashem Sezavar [6 ]
Mottaghi, Azadeh [6 ]
机构：
[1] Iran Univ Med Sci, Sch Med, Tehran, Iran
[2] Iran Univ Med Sci, Sch Med, Prevent Med & Publ Hlth Res Ctr, Dept Community & Family Med, Tehran, Iran
[3] Iran Univ Med Sci, Inst Endocrinol & Metab, Endocrine Res Ctr, Tehran, Iran
[4] Iran Univ Med Sci, Trauma & Injury Res Ctr, Tehran, Iran
[5] Iran Univ Med Sci, Sch Publ Hlth, Dept Biostat, Tehran, Iran
[6] Iran Univ Med Sci, Inst Endocrinol & Metab, Res Ctr Prevent Cardiovasc Dis, Tehran, Iran
来源：
OBESITY SURGERY | 2019年 / 29卷 / 02期
关键词：
Obesity; Bariatric surgery; Metabolic; Weight; Insulin resistance; Y GASTRIC BYPASS; PLASMINOGEN-ACTIVATOR INHIBITOR-1; SOLUBLE LEPTIN RECEPTOR; WEIGHT-LOSS; INSULIN-RESISTANCE; SLEEVE GASTRECTOMY; ADIPOSE-TISSUE; MORBID-OBESITY; FATTY-ACIDS; SHORT-TERM;
D O I：
10.1007/s11695-018-3550-z
中图分类号：
R61 [外科手术学];
学科分类号：
摘要：
BackgroundConsidering conflicting results on the consequences of all types of obesity surgery, we were to summarize them via a systematic review.MethodsElectronic literature search was done via scientific search engines. After the removal of duplicates and selection of articles of interest, 771 studies were included.ResultsInsulin resistance indicators were significantly improved after bariatric surgery. Leptin was also significantly decreased while adiponectin was significantly increased. Although the level of metabolic hormones changed after bariatric surgery, they were not statistically significant. Inflammation indicators were significantly decreased. Significant reduction was also detected in PAI-1 and sICAM-1.ConclusionsBariatric surgery is beneficial in morbidly obese patients. Although treating obesity in a surgical way may cause some complications, the weight loss is generally safe and effective.
引用
收藏
页码：651 / 690
页数：40
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