Fast and efficient solvent-free Passerini reaction

被引：38

作者：

Bousquet, Till ^{[1
,2
,3
]}

Jida, Mouhamad ^{[1
,3
,4
]}

Soueidan, Mohamad ^{[1
,2
,3
]}

Deprez-Poulain, Rebecca ^{[1
,3
,4
]}

Agbossou-Niedercorn, Francine ^{[1
,2
,3
]}

Pelinski, Lydie ^{[1
,2
,3
]}

机构：

[1] Univ Lille Nord France, Lille, France

[2] Univ Lille 1, Unite Catalyse & Chim Solide, CNRS, UMR 8181, F-59655 Villeneuve Dascq, France

[3] PRIM, F-59000 Lille, France

[4] INSERM, Fac Pharm, U761, F-59006 Lille, France

来源：

TETRAHEDRON LETTERS | 2012年 / 53卷 / 03期

关键词：

Passerini reaction; Solvent free; High temperature; MULTICOMPONENT REACTIONS;

D O I：

10.1016/j.tetlet.2011.11.028

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A Passerini three component condensation between a carboxylic acid, an aldehyde, and an isocyanide at high temperature under solvent-free conditions was developed. This methodology allows the formation of a broad range of alpha-acyloxyamides in excellent yields in short reaction times. (C) 2011 Elsevier Ltd. All rights reserved.

引用

页码：306 / 308

页数：3

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