Rhino-orbito-cerebral mucormycosis caused by Rhizopus microsporus var. microsporus in a diabetic patient with COVID-19

被引:1
作者
Munhoz, Sandy Daniele [1 ]
Lellis, Rute Facchini [1 ,2 ]
Carvalho Reis, Ana Paula [1 ,3 ,4 ]
Barbaro Del Negro, Gilda Maria [1 ,3 ,4 ]
Teixeira Sousa, Maria Gloria [1 ,3 ,4 ]
Veasey, John Verrinder [1 ,5 ]
机构
[1] Hosp Santa Casa Sao Paulo, Dermatol Clin, Sao Paulo, SP, Brazil
[2] Hosp Santa Casa Sao Paulo, Pathol Lab, Sao Paulo, SP, Brazil
[3] Univ Sao Paulo, Hosp Clin, Fac Med, Div Clin Dermatol,Med Mycol Lab LIM 53, Sao Paulo, SP, Brazil
[4] Univ Sao Paulo, Inst Med Trop Sao Paulo, Sao Paulo, SP, Brazil
[5] Santa Casa Sao Paulo, Med Sci Coll, Sao Paulo, SP, Brazil
关键词
Amphotericin B; Coronavirus; COVID-19; Diabetes mellitus; Diagnosis; Mucormycosis;
D O I
10.1016/j.abd.2022.02.001
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
COVID-19 disease caused by the SARS-CoV-2 coronavirus causes a wide range of clinical manifestations, ranging from mild to severe, with the main ones affecting the respiratory tract, such as pneumonia. In patients with greater severity, the high frequency of bacterial and fungal coinfection stands out, a situation related both to the patient's pre-existing comorbidities and due to the hospitalization itself. Cases of mucormycosis associated with COVID-19 were highlighted in the lay and scientific media, with the increase in mycosis cases being directly and indirectly attributed to the viral infection. This report describes a case of rhino-orbito-cerebral mucormycosis in a diabetic patient hospitalized for COVID-19, whose diagnosis was confirmed by identifying the agent Rhizopus microsporus var. microsporus through culture for fungi and PCR examination. (C) 2022 Sociedade Brasileira de Dermatologia. Published by Elsevier Espana, S.L.U.
引用
收藏
页码:501 / 504
页数:4
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