Technical Note: GATE-RTion: a GATE/Geant4 release for clinical applications in scanned ion beam therapy

被引:29
作者
Grevillot, L. [1 ]
Boersma, D. J. [1 ,2 ]
Fuchs, H. [1 ,3 ,4 ]
Aitkenhead, A. [5 ]
Elia, A. [1 ]
Bolsa, M. [1 ]
Winterhalter, C. [6 ]
Vidal, M. [7 ]
Jan, S. [8 ]
Pietrzyk, U. [9 ]
Maigne, L. [10 ]
Sarrut, D. [11 ]
机构
[1] MedAustron Ion Therapy Ctr, Marie Curie Str 5, A-2700 Wiener Neustadt, Austria
[2] ACMIT Gmbh, Viktor Kaplan Str 2-1, A-2700 Wiener Neustadt, Austria
[3] Med Univ Vienna, Vienna, Austria
[4] Med Univ Vienna, Dept Radiat Therapy, AKH Vienna, Vienna, Austria
[5] Univ Manchester, Christie NHS Fdn Trust, Manchester Canc Res Ctr, Div Canc Sci, Manchester, Lancs, England
[6] Univ Manchester, Christie NHS Fdn Trust, Div Canc Sci, Manchester, Lancs, England
[7] Univ Cote Azur Federat Claude Lalanne, Ctr Antoine LACASSAGNE, Nice, France
[8] Univ Paris Saclay, INSERM, UMR BioMaps, CEA,CNRS, 4 Pl Gen Leclerc, F-91401 Orsay, France
[9] Univ Wuppertal, Wuppertal, Germany
[10] Univ Clermont Auvergne, CNRS, IN2P3, UMR6533,Lab Phys Clermont, 4 Ave Blaise Pascal TSA 60026 CS 60026, F-63178 Aubiere, France
[11] Univ Lyon 1, Univ Lyon, CREATIS, CNRS,UMR5220,Inserm,U1044,INSA Lyon, Lyon, France
基金
英国科学技术设施理事会; 英国工程与自然科学研究理事会;
关键词
clinical; GATE; Geant4; ion beam therapy; Independent dose calculation; Monte Carlo simulation; MONTE-CARLO SIMULATIONS; PROTON THERAPY; PLATFORM; GEANT4; FLUKA; MODEL; DISTRIBUTIONS; VERIFICATION; DELIVERY; DESIGN;
D O I
10.1002/mp.14242
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
Purpose GATE-RTion is a validated version of GATE for clinical use in the field of light ion beam therapy. This paper describes the GATE-RTion project and illustrates its potential through clinical applications developed in three European centers delivering scanned proton and carbon ion treatments. Methods GATE-RTion is a collaborative framework provided by the OpenGATE collaboration. It contains a validated GATE release based on a specific Geant4 version, a set of tools to integrate GATE into a clinical environment and a network for clinical users. Results Three applications are presented: Proton radiography at the Centre Antoine Lacassagne (Nice, France); Independent dose calculation for proton therapy at the Christie NHS Foundation Trust (Manchester, UK); Independent dose calculation for protons and carbon ions at the MedAustron Ion Therapy center (Wiener Neustadt, Austria). Conclusions GATE-RTion builds the bridge between researchers and clinical users from the OpenGATE collaboration in the field of Light Ion Beam Therapy. The applications presented in three European facilities using three completely different machines (three different vendors, cyclotron- and synchrotron-based systems, protons, and carbon ions) demonstrate the relevance and versatility of this project.
引用
收藏
页码:3675 / 3681
页数:7
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