Current Role of Allogeneic Stem Cell Transplantation in Multiple Myeloma

被引：5

作者：

Claveau, Jean-Sebastien ^{[1
]}

Buadi, Francis K. ^{[1
]}

Kumar, Shaji ^{[1
]}

机构：

[1] Mayo Clin, Div Hematol, 200 First St SW, Rochester, MN 55905 USA

来源：

ONCOLOGY AND THERAPY | 2022年 / 10卷 / 01期

关键词：

Multiple myeloma; Allogeneic transplantation; Chronic graft-versus-host disease; CAR-T cell therapy; BONE-MARROW-TRANSPLANTATION; TERM-FOLLOW-UP; REDUCED-INTENSITY; AUTOLOGOUS TRANSPLANTATION; LENALIDOMIDE MAINTENANCE; COMORBIDITY INDEX; EUROPEAN GROUP; HEMATOLOGIC MALIGNANCIES; CONDITIONING REGIMEN; CONSENSUS STATEMENT;

D O I：

10.1007/s40487-022-00195-3

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Major progress in the treatment of multiple myeloma has been made in the last several years. However, myeloma remains incurable and patients with high-risk cytogenetics or advanced stage disease have an even worsen survival. Only allogeneic transplantation may have curative potential in some patients. However, the high non-relapse mortality and incidence of chronic graft-versus-host disease have raised controversy regarding this procedure. In this review, we will address the role of upfront and delayed allogeneic transplant.

引用

页码：105 / 122

页数：18

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