Robust estimation of generalized partially linear model for longitudinal data with dropouts

被引:9
作者
Qin, Guoyou [1 ]
Zhu, Zhongyi [2 ]
Fung, Wing K. [3 ]
机构
[1] Fudan Univ, Sch Publ Hlth & Key Lab Publ Hlth Safety, Dept Biostat, Shanghai 200032, Peoples R China
[2] Fudan Univ, Dept Stat, Shanghai 200433, Peoples R China
[3] Univ Hong Kong, Dept Stat & Actuarial Sci, Pokfulam Rd, Hong Kong, Hong Kong, Peoples R China
基金
中国国家自然科学基金;
关键词
Dropouts; Partially linear models; Regression splines; Robustness; ESTIMATING EQUATIONS; REGRESSION-MODELS; CLUSTERED DATA; MIXED MODELS;
D O I
10.1007/s10463-015-0519-8
中图分类号
O21 [概率论与数理统计]; C8 [统计学];
学科分类号
020208 ; 070103 ; 0714 ;
摘要
In this paper, we study the robust estimation of generalized partially linear models (GPLMs) for longitudinal data with dropouts. We aim at achieving robustness against outliers. To this end, a weighted likelihood method is first proposed to obtain the robust estimation of the parameters involved in the dropout model for describing the missing process. Then, a robust inverse probability-weighted generalized estimating equation is developed to achieve robust estimation of the mean model. To approximate the nonparametric function in the GPLM, a regression spline smoothing method is adopted which can linearize the nonparametric function such that statistical inference can be conducted operationally as if a generalized linear model was used. The asymptotic properties of the proposed estimator are established under some regularity conditions, and simulation studies show the robustness of the proposed estimator. In the end, the proposed method is applied to analyze a real data set.
引用
收藏
页码:977 / 1000
页数:24
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