Flow cytometric measurement of STAT1 and STAT3 phosphorylation in CD4+ and CD8+ T cells-clinical applications in primary immunodeficiency diagnostics

被引:8
作者
Bitar, Michael [1 ]
Boldt, Andreas [1 ]
Binder, Stefanie [1 ]
Borte, Michael [2 ]
Kentouche, Karim [3 ]
Borte, Stephan [2 ,4 ]
Sack, Ulrich [1 ]
机构
[1] Univ Leipzig, Inst Clin Immunol, Med Fac, Leipzig, Germany
[2] Hosp St Georg gGmbH Leipzig, Immuno Deficiency Ctr Leipzig IDCL, Jeffrey Modell Diagnost & Res Ctr Primary Immunod, Leipzig, Germany
[3] Jena Univ Hosp, Dept Pediat, Jena, Germany
[4] Karolinska Univ, Hosp Huddinge, Karolinska Inst, Dept Lab Med,Div Clin Immunol & Transfus Med, Stockholm, Sweden
关键词
CHRONIC MUCOCUTANEOUS CANDIDIASIS; EXPRESSION;
D O I
10.1016/j.jaci.2017.05.017
中图分类号
R392 [医学免疫学];
学科分类号
100102 ;
摘要
[No abstract available]
引用
收藏
页码:1439 / +
页数:12
相关论文
共 10 条
[1]   Regulated expression of gp130 and IL-6 receptor α chain in T cell maturation and activation [J].
Betz, UAK ;
Müller, W .
INTERNATIONAL IMMUNOLOGY, 1998, 10 (08) :1175-1184
[2]   Inborn Errors of Human JAKs and STATs [J].
Casanova, Jean-Laurent ;
Holland, Steven M. ;
Notarangelo, Luigi D. .
IMMUNITY, 2012, 36 (04) :515-528
[3]   A partial form of recessive STAT1 deficiency in humans [J].
Chapgier, Ariane ;
Kong, Xiao-Fei ;
Boisson-Dupuis, Stephanie ;
Jouanguy, Emmanuelle ;
Averbuch, Diana ;
Feinberg, Jacqueline ;
Zhang, Shen-Ying ;
Bustamante, Jacinta ;
Vogt, Guillaume ;
Lejeune, Julien ;
Mayola, Eleonore ;
de Beaucoudrey, Ludovic ;
Abel, Laurent ;
Engelhard, Dan ;
Casanova, Jean-Laurent .
JOURNAL OF CLINICAL INVESTIGATION, 2009, 119 (06) :1502-1514
[4]   Signaling by STATs [J].
Ivashkiv, LB ;
Hu, XY .
ARTHRITIS RESEARCH & THERAPY, 2004, 6 (04) :159-168
[5]   A flow cytometry technique to study intracellular signals NF-κB and STAT3 in peripheral blood mononuclear cells [J].
Lafarge, Sandrine ;
Hamzeh-Cognasse, Hind ;
Chavarin, Patricia ;
Genin, Christian ;
Garraud, Olivier ;
Cognasse, Fabrice .
BMC MOLECULAR BIOLOGY, 2007, 8
[6]   Gain-of-function human STAT1 mutations impair IL-17 immunity and underlie chronic mucocutaneous candidiasis [J].
Liu, Luyan ;
Okada, Satoshi ;
Kong, Xiao-Fei ;
Kreins, Alexandra Y. ;
Cypowyj, Sophie ;
Abhyankar, Avinash ;
Toubiana, Julie ;
Itan, Yuval ;
Audry, Magali ;
Nitschke, Patrick ;
Masson, Cecile ;
Toth, Beata ;
Flatot, Jerome ;
Migaud, Melanie ;
Chrabieh, Maya ;
Kochetkov, Tatiana ;
Bolze, Alexandre ;
Borghesi, Alessandro ;
Toulon, Antoine ;
Hiller, Julia ;
Eyerich, Stefanie ;
Eyerich, Kilian ;
Gulacsy, Vera ;
Chernyshova, Ludmyla ;
Chernyshov, Viktor ;
Bondarenko, Anastasia ;
Cortes Grimaldo, Rosa Maria ;
Blancas-Galicia, Lizbeth ;
Madrigal Beas, Ileana Maria ;
Roesler, Joachim ;
Magdorf, Klaus ;
Engelhard, Dan ;
Thumerelle, Caroline ;
Burgel, Pierre-Regis ;
Hoernes, Miriam ;
Drexel, Barbara ;
Seger, Reinhard ;
Kusuma, Theresia ;
Jansson, Annette F. ;
Sawalle-Belohradsky, Julie ;
Belohradsky, Bernd ;
Jouanguy, Emmanuelle ;
Bustamante, Jacinta ;
Bue, Melanie ;
Karin, Nathan ;
Wildbaum, Gizi ;
Bodemer, Christine ;
Lortholary, Olivier ;
Fischer, Alain ;
Blanche, Stephane .
JOURNAL OF EXPERIMENTAL MEDICINE, 2011, 208 (08) :1635-1648
[7]   Differential expression of CD126 and CD130 mediates different STAT-3 phosphorylation in CD4+CD25- and CD25high regulatory t cells [J].
Oberg, HH ;
Wesch, D ;
Grüssel, S ;
Rose-John, S ;
Kabelitz, D .
INTERNATIONAL IMMUNOLOGY, 2006, 18 (04) :555-563
[8]   Accreditation of flow cytometry in Europe [J].
Sack, Ulrich ;
Barnett, David ;
Demirel, Gulderen Yanikkaya ;
Fossat, Chantal ;
Fricke, Stephan ;
Kafassi, Nikolitsa ;
Nebe, Thomas ;
Psarra, Katherina ;
Steinmann, Joerg ;
Lambert, Claude .
CYTOMETRY PART B-CLINICAL CYTOMETRY, 2013, 84B (03) :135-142
[9]   An update on the hyper-IgE syndromes [J].
Yong, Patrick F. K. ;
Freeman, Alexandra F. ;
Engelhardt, Karin R. ;
Holland, Steven ;
Puck, Jennifer M. ;
Grimbacher, Bodo .
ARTHRITIS RESEARCH & THERAPY, 2012, 14 (06)
[10]   Gain-of-function STAT1 mutations impair STAT3 activity in patients with chronic mucocutaneous candidiasis (CMC) [J].
Zheng, Jie ;
de Veerdonk, Frank L. van ;
Crossland, Katherine L. ;
Smeekens, Sanne P. ;
Chan, Chun M. ;
Al Shehri, Tariq ;
Abinun, Mario ;
Gennery, Andrew R. ;
Mann, Jelena ;
Lendrem, Dennis W. ;
Netea, Mihai G. ;
Rowan, Andrew D. ;
Lilic, Desa .
EUROPEAN JOURNAL OF IMMUNOLOGY, 2015, 45 (10) :2834-2846