Deception through Mimicry: A Cellular Antiviral Strategy

被引：0
作者：
Wu, Nicholas C. [1 ]
Ward, Andrew B. [1 ]
机构：
[1] Scripps Res Inst, Dept Integrat Struct & Computat Biol, La Jolla, CA 92037 USA
来源：
CELL | 2018年 / 175卷 / 07期
关键词：
D O I：
10.1016/j.cell.2018.11.033
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Viruses use mimicry to hijack cellular machinery, but can human cells use mimicry as an antiviral approach? Batra et al. identify a novel antiviral restriction factor, RBBP6, by characterizing the cellular interactome of Ebola virus. RBBP6 targets the Ebola virus transcription factor VP30 by mimicking the binding of Ebola virus nucleoprotein.
引用
收藏
页码：1728 / 1729
页数：2
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