Assessment of nutritional status using biochemical and anthropometric variables in a nutritional intervention study of women with hip fracture

Background & Aims. The aim of this study of women with hip fracture was to describe nutritional status with biochemical markers and anthropometric variables, and to evaluate the effect of nutritional intervention with the intention of increasing protein and energy intake. Methods: The first consecutive 44 women were included, and used as controls. The next 44 were matched for age, fracture and mental state. Anthropometric variables, IGF-I, hormones and serum albumin were collected 4-6 days (baseline), 1 and 3 months after surgery. Twenty-four women filled out a 7-day food record. Results: At baseline, one fourth had BMI < 20 kg/m(2) and subnormal triceps skinfold thickness. Baseline serum albumin, IGF-I and growth hormone levels were low, probably as an acute response to trauma. Women with BMI < 20 kg/m(2) had lower IGF-I levels compared to those with higher BMI. At 3 months, one-third of both groups were protein and energy malnourished. The intervention group obtained higher daily energy percentage from fat but none of the groups reached their calculated energy need. Conclusions: Using biochemical markers in the acute postoperative situation to assess nutritional status is not recommended. The intervention had no impact on anthropometric or biochemical variables. (C) 2001 Harcourt Publishers Ltd.