Heart Failure with Preserved Ejection Fraction in Women

被引：39

作者：

Tibrewala, Anjan ^{[1
]}

Yancy, Clyde W. ^{[1
]}

机构：

[1] Northwestern Univ, Feinberg Sch Med, Dept Internal Med, Div Cardiol, Chicago, IL 60611 USA

来源：

HEART FAILURE CLINICS | 2019年 / 15卷 / 01期

关键词：

Heart failure with preserved ejection fraction; Diastolic heart failure; Sex differences; Women; ALL-CAUSE MORTALITY; SEX-DIFFERENCES; CLINICAL CHARACTERISTICS; RISK; OUTCOMES; MEN; HOSPITALIZATION; ASSOCIATION; CANDESARTAN; DYSFUNCTION;

D O I：

10.1016/j.hfc.2018.08.002

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Heart failure with preserved ejection fraction (HFpEF) is an increasingly prevalent condition, particularly in women. Comorbidities, including older age, obesity, diabetes mellitus, hypertension, and hyperlipidemia, are risk factors and define phenotypic profiles of HFpEF in women. The condition has a relatively high burden of morbidity and mortality, with phenotypic profiles potentially characterizing risk of hospitalization and mortality. Based on limited data, nonpharmacologic and pharmacologic treatments may provide benefit; however, compelling evidence-based, disease-modifying treatments are needed. Many unanswered questions about HFpEF in women warrant further investigation to improve understanding of the disease and provide better patient care.

引用

页码：9 / 18

页数：10

共 45 条

[1]

Benjamin EJ, 2017, CIRCULATION, V135, pE146, DOI [10.1161/CIR.0000000000000485, 10.1161/CIR.0000000000000558, 10.1161/CIR.0000000000000530]

[2] The survival of patients with heart failure with preserved or reduced left ventricular ejection fraction: an individual patient data meta-analysis [J].

Berry, C. ;

Doughty, R. N. ;

Granger, C. ;

Kober, L. ;

Massie, B. ;

McAlister, F. ;

McMurray, J. ;

Pocock, S. ;

Poppe, K. ;

Swedberg, K. ;

Somaratne, J. ;

Whalley, G. A. ;

Ahmed, A. ;

Andersson, B. ;

Bayes-Genis, A. ;

Berry, C. ;

Cowie, M. ;

Cubbon, R. ;

Doughty, R. N. ;

Ezekowitz, J. ;

Gonzalez-Juanatey, J. ;

Gorini, M. ;

Gotsman, I. ;

Grigorian-Shamagian, L. ;

Guazzi, M. ;

Kearney, M. ;

Kober, L. ;

Komajda, M. ;

di Lenarda, A. ;

Lenzen, M. ;

Lucci, D. ;

Macin, S. ;

Madsen, B. ;

Maggioni, A. ;

Martinez-Selles, M. ;

McAlister, F. ;

Oliva, F. ;

Poppe, K. ;

Rich, M. ;

Richards, M. ;

Senni, M. ;

Squire, I. ;

Taffet, G. ;

Tarantini, L. ;

Tribouilloy, C. ;

Troughton, R. ;

Tsutsui, H. ;

Whalley, G. A. ;

Doughty, R. N. ;

Earle, N. .

EUROPEAN HEART JOURNAL, 2012, 33 (14) :1750-1757

[3] Heart failure with preserved and reduced ejection fraction: different risk profiles for different diseases [J].

Borlaug, Barry A. .

EUROPEAN HEART JOURNAL, 2013, 34 (19) :1393-1395

[4] Multimorbidity in Heart Failure: A Community Perspective [J].

Chamberlain, Alanna M. ;

St Sauver, Jennifer L. ;

Gerber, Yariv ;

Manemann, Sheila M. ;

Boyd, Cynthia M. ;

Dunlay, Shannon M. ;

Rocca, Walter A. ;

Rutten, Lila J. Finney ;

Jiang, Ruoxiang ;

Weston, Susan A. ;

Roger, Veronique L. .

AMERICAN JOURNAL OF MEDICINE, 2015, 128 (01) :38-45

[5] Incidence and Survival of Hospitalized Acute Decompensated Heart Failure in Four US Communities (from the Atherosclerosis Risk in Communities Study) [J].

Chang, Patricia P. ;

Chambless, Lloyd E. ;

Shahar, Eyal ;

Bertoni, Alain G. ;

Russell, Stuart D. ;

Ni, Hanyu ;

He, Max ;

Mosley, Thomas H. ;

Wagenknecht, Lynne E. ;

Samdarshi, Tandaw E. ;

Wruck, Lisa M. ;

Rosamond, Wayne D. .

AMERICAN JOURNAL OF CARDIOLOGY, 2014, 113 (03) :504-510

[6] Correlates of Echocardiographic Indices of Cardiac Remodeling Over the Adult Life Course Longitudinal Observations From the Framingham Heart Study [J].

Cheng, Susan ;

Xanthakis, Vanessa ;

Sullivan, Lisa M. ;

Lieb, Wolfgang ;

Massaro, Joseph ;

Aragam, Jayashri ;

Benjamin, Emelia J. ;

Vasan, Ramachandran S. .

CIRCULATION, 2010, 122 (06) :570-U37

[7] Comparison of morbidity in women versus men with heart failure and preserved ejection fraction [J].

Deswal, A ;

Bozkurt, B .

AMERICAN JOURNAL OF CARDIOLOGY, 2006, 97 (08) :1228-1231

[8] Risk Factors for Incident Hospitalized Heart Failure With Preserved Versus Reduced Ejection Fraction in a Multiracial Cohort of Postmenopausal Women [J].

Eaton, Charles B. ;

Pettinger, Mary ;

Rossouw, Jacques ;

Martin, Lisa Warsinger ;

Foraker, Randi ;

Quddus, Abdullah ;

Liu, Simin ;

Wampler, Nina S. ;

Wu, Wen-Chih Hank ;

Manson, JoAnn E. ;

Margolis, Karen ;

Johnson, Karen C. ;

Allison, Matthew ;

Corbie-Smith, Giselle ;

Rosamond, Wayne ;

Breathett, Khadijah ;

Klein, Liviu .

CIRCULATION-HEART FAILURE, 2016, 9 (10)

[9]

Ebong IA, 2014, MENOPAUSE, V21, P585, DOI [10.1097/gme.0000000000000138, 10.1097/GME.0000000000000138]

[10] Heart failure outcomes with empagliflozin in patients with type 2 diabetes at high cardiovascular risk: results of the EMPA-REG OUTCOME® trial [J].

Fitchett, David ;

Zinman, Bernard ;

Wanner, Christoph ;

Lachin, John M. ;

Hantel, Stefan ;

Salsali, Afshin ;

Johansen, Odd Erik ;

Woerle, Hans J. ;

Broedl, Uli C. ;

Inzucchi, Silvio E. ;

Aizenberg, D. ;

Ulla, M. ;

Waitman, J. ;

De Loredo, L. ;

Farias, J. ;

Fideleff, H. ;

Lagrutta, M. ;

Maldonado, N. ;

Colombo, H. ;

Ferre Pacora, F. ;

Wasserman, A. ;

Maffei, L. ;

Lehman, R. ;

Selvanayagam, J. ;

d'Emden, M. ;

Fasching, P. ;

Paulweber, B. ;

Toplak, H. ;

Luger, A. ;

Drexel, H. ;

Prager, R. ;

Schnack, C. ;

Schernthaner, G. ;

Fliesser-Goerzer, E. ;

Kaser, S. ;

Scheen, A. ;

Van Gaal, L. ;

Hollanders, G. ;

Kockaerts, Y. ;

Capiau, L. ;

Chachati, A. ;

Persu, A. ;

Hermans, M. ;

Vantroyen, D. ;

Vercammen, C. ;

Van de Borne, P. ;

Mathieu, C. ;

Benhalima, K. ;

Lienart, F. ;

Mortelmans, J. .

EUROPEAN HEART JOURNAL, 2016, 37 (19) :1526-1534

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