The Introduction and Clinical Use of Cardiac-Specific Troponin Assays

被引：14

作者：

Antman, Elliott M. ^{[1
]}

机构：

[1] Brigham & Womens Hosp, TIMI Study Grp, 75 Francis St, Boston, MA 02115 USA

来源：

CLINICAL PHARMACOLOGY & THERAPEUTICS | 2018年 / 103卷 / 01期

关键词：

D O I：

10.1002/cpt.773

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

The earliest biomarkers introduced to diagnose myocardial infarction (MI) such as aspartate aminotransferase (AST) and lactic dehydrogenase (LDH) lacked cardiac specificity and were replaced by creatine kinase (CK), the CK-MB isoenzyme, and ultimately the cardiac-specific troponins (cTnT and cTnI). This has opened up the possibilities of ruling out MI more rapidly and also identifying patients with a chronic elevation of cTn and a poor prognosis in a range of cardiac conditions.

引用

页码：31 / 33

页数：3

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