Glutathione S-transferase activity in normal and malignant cells and tissues: a comparative study

被引：0

作者：

Stankov, K ^{[1
]}

Kovacevic, Z ^{[1
]}

Bajin-Katic, K ^{[1
]}

Stankov, S ^{[1
]}

Vukmirovic, S ^{[1
]}

机构：

[1] Univ Novi Sad, Dept Biochem, Med Fac Novi Sad, YU-21000 Novi Sad, Yugoslavia

来源：

CHEMICO-BIOLOGICAL INTERACTIONS | 2001年 / 133卷 / 1-3期

关键词：

glutathione transferase; oxidative stress; malignant cells; microsomal fraction;

D O I：

暂无

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Measurement of glutathione S-transferase (GST) activity in normal and malignant cells and tissues was performed in the form of comparative study. The results of this study may be fundamental for further analysis of the influence of different pro-oxidants and antitumour drugs on examined cells and organs. Determined levels of GST specific activity may indicate that antioxidative capacity and protective potential of malignant cells are decreased in comparison with normal cells and tissues, with the important exception that malignant cells possess the ability of enzyme induction in conditions of oxidative stress. (C) 2001 Elsevier Science Ireland Ltd. All rights reserved.

引用

页码：345 / 348

页数：4