Design, synthesis, characterization and evaluation of 1-aminomethyl-3-{4′-(4"-nitrobenzyloxy)benzoylhydrazono}-5/6-chloroindolin-2-ones

被引：0
|
作者：
Harrison, Darwin Anil [1 ]
Rastogi, Nisheeth [1 ]
Rahman, Masihur [2 ]
机构：
[1] Lucknow Christian Degree Coll, Dept Chem, Dr WE Bauer Res Lab, Lucknow 226018, Uttar Pradesh, India
[2] Integral Univ, Dept Chem, Lucknow 226026, Uttar Pradesh, India
来源：
JOURNAL OF THE INDIAN CHEMICAL SOCIETY | 2014年 / 91卷 / 02期
关键词：
Indole-2,3-dione; Schiff base; Mannich base; aminomethylation; antifungal activity;
D O I：
暂无
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A new series of 1-aminomethyl-3-{4'-(4 ''-nitrobenzyloxy)benzoylhydrazono}-5/6-chloroindolin-2-ones (Mannich bases) have been synthesized and screened for their antifungal potential against human pathogenic fungi. The structures of the compounds have been elucidated with the help of elemental analysis and spectral data (IR, H-1 NMR and Mass).
引用
收藏
页码：319 / 324
页数：6
相关论文
共 50 条
  • [41] Synthesis and Antimicrobial Activity of 5-(Het)aryl-3-hydroxy-1-hydroxyethyl-4-(thienyl-2-carbonyl)-3-pyrrolin-2-ones
    Gein, V. L.
    Rubtsova, D. D.
    Bobyleva, A. A.
    Ryabova, O. V.
    Novikova, V. V.
    Kasimova, N. N.
    Yankin, A. N.
    RUSSIAN JOURNAL OF GENERAL CHEMISTRY, 2020, 90 (07) : 1222 - 1228
  • [42] Synthesis, Partition coefficient and antibacterial activity of 3′-aryl-6′-phenyl(substituted)-cis-5′a,6′-dihydrospiro[3H-indole-3,4′-thiozolo(5′,1′-c)-isoxazolo-2-(1H)-ones]
    Sahu, S. K.
    Mishra, S. K.
    Banerjee, M.
    Panda, P. K.
    Misro, P. K.
    JOURNAL OF THE INDIAN CHEMICAL SOCIETY, 2006, 83 (07) : 725 - 727
  • [43] Synthesis of aminomethyl derivatives of 3-methyl-4,7-dihydro-3H-imidazo[4,5-d][1,2,3]triazin-4-one
    G. L. Rusinov
    R. I. Ishmetova
    I. S. Selezneva
    T. A. Kalugina
    Russian Journal of Electrochemistry, 2000, 36 : 873 - 876
  • [44] Synthesis of aminomethyl derivatives of 3-methyl-4,7-dihydro-3H-imidazo[4,5-d][1,2,3]triazin-4-one
    Rusinov, GL
    Ishmetova, RI
    Selezneva, IS
    Kalugina, TA
    RUSSIAN JOURNAL OF ORGANIC CHEMISTRY, 2000, 36 (06) : 873 - 876
  • [45] Synthesis and Antimicrobial Activity of 5-(Het)aryl-3-hydroxy-1-hydroxyethyl-4-(thienyl-2-carbonyl)-3-pyrrolin-2-ones
    V. L. Gein
    D. D. Rubtsova
    A. A. Bobyleva
    O. V. Ryabova
    V. V. Novikova
    N. N. Kasimova
    A. N. Yankin
    Russian Journal of General Chemistry, 2020, 90 : 1222 - 1228
  • [46] Synthesis and evaluation of novel 3a,9a-dihydro-1-ethoxycarbonyl-1-cyclopenteno[5,4-b]benzopyran-4-ones as antifungal agents
    Goel, Richa
    Sharma, Vishal
    Budhiraja, Abhishek
    Ishar, Mohan Paul S.
    BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2012, 22 (14) : 4665 - 4667
  • [47] Synthesis and Antifungal Activity of Some Novel (E)-2, 3-Dihydro-3-[(phenylamino) methylene]-4H-1-benzothiopyran-4-ones
    Liu Xiao-Ming
    Yang Geng-Liang
    Song Ya-Li
    Liu Jie-Jie
    Wang Yang
    Zhang Dong-Nuan
    LETTERS IN ORGANIC CHEMISTRY, 2013, 10 (03) : 228 - 234
  • [48] A convenient 'one-pot' synthesis and in vitro microbiological evaluation of novel 2,7-diaryl-[1,4]-diazepan-5-ones
    Gopalakrishnan, M.
    Sureshkumar, P.
    Thanusu, J.
    Kanagarajan, V.
    Govindaraju, R.
    Jayasri, G.
    JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, 2007, 22 (06) : 709 - 715
  • [49] Synthesis and In Vitro Antioxidant Evaluation of Some Novel 4, 5-Dihydro-1H-1, 2, 4-triazol-5-one Derivatives
    Kol, O. Gursoy
    Yuksek, H.
    E-JOURNAL OF CHEMISTRY, 2010, 7 (01) : 123 - 136
  • [50] Synthesis and antifungal activity of some new derivatives of 5-{4′-(2",4"-dichlorobenzyloxy)-phenyl}-1,3,4-oxadiazole-2(3H)-thione
    Rastogi, Nisheeth
    Harrison, Darwin Anil
    JOURNAL OF THE INDIAN CHEMICAL SOCIETY, 2012, 89 (11) : 1543 - 1550
12345