NUCLEAR DATA MEASUREMENT OF 186RE PRODUCTION VIA VARIOUS REACTIONS

Rhenium-186, having a half-life of 90.64 h, is an important radionuclide, used in metabolic radiotherapy and radio immunotherapy. Re-186 hydroxyethylidene diphosphonate (HEDP) is a new compound used for the palliation of painful skeletal metastases. Its production is achieved via charged-particle-induced reactions; the data are available in EXFOR library. For the work discussed in this paper, production of Re-186 was done via W-nat(p,n)Re-186 nuclear reaction. Pellets of W-nat were used as targets and were irradiated with 15, 17.5, 20, 22.5, 25 MeV proton beams at 5 mu A current. The radiochemical separation was performed by the ion exchange chromatography method. The production yield achieved at 25 MeV was 1.91 MBq.mu A(-1).h(-1). Excitation functions for the Re-186 radionuclide, via (186)w(p,n)Re-186 and W-186(d,2n)Re-186 reactions were calculated by ALICE-ASH and TALYS-1.0 codes to validate and fit the experimental data and to obtain a recommended set of data for W-186(p,n) Re-186 reaction. Required thickness of the targets was obtained by SRIM code for each reaction.