Syntheses and characterization of a new class of mono- and heterodinuclear derivatives of boron derived from Schiff bases

Reactions of 2-isopropoxy-1,3,2-benzodioxaborole with equivalent amounts of Schiff base ligands having two hydroxyl groups (1a-3a) yield mononuclear derivatives with one residual hydroxy group. The reactions of these mononuclear derivatives with hexamethyldisilazane in a 2: 1 ratio yield heterodinuclear derivatives. All these newly synthesized derivatives have been characterized by elemental analyses and molecular weight measurements. Tentative structures have been proposed on the basis of IR and NMR (H-1, C-13, B-11,Si-29)spectral data and Fab-mass studies. Schiff bases and their corresponding mono- and heterodinuclear derivatives of boron have also been screened for antifungal activities. Copyright (C) 2010 John Wiley & Sons, Ltd.