Influence of GABAergic inhibition on concerted activity between the ganglion cells

被引：10

作者：

Jing, Wei ^{[1
]}

Liu, Wen-Zhong ^{[1
]}

Gong, Xin-Wei ^{[1
]}

Gong, Hai-Qing ^{[1
]}

Liang, Pei-Ji ^{[1
]}

机构：

[1] Shanghai Jiao Tong Univ, Dept Biomed Engn, Shanghai 200240, Peoples R China

来源：

NEUROREPORT | 2010年 / 21卷 / 12期

关键词：

bullfrog retina; cross-correlation; dimming detectors; GABA(A) receptor; multi-electrode recording; VOLTAGE-DEPENDENCE; RETINA; FROGS;

D O I：

10.1097/WNR.0b013e32833c5b50

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

In this study, the spike discharges of one subtype of bullfrog retinal ganglion cells (dimming detectors) in response to repetitive full field light-OFF stimuli were recorded using multi-electrode arrays. Two different types of concerted activity (precise synchronization and correlated activity) could be distinguished. The nearby cells with overlapped receptive field areas often fired in synchrony, whereas the correlated activity was mainly observed from remote cell pairs with separated receptive fields. After the bicuculline application, the strength of the synchronized activity was increased whereas that of the correlated activity was decreased. These results suggest that the activation of GABA(A)-receptor-mediated inhibitory pathways differentially modulates the concerted firing of the ganglion cells. NeuroReport 21:797-801 (C) 2010 Wolters Kluwer Health | Lippincott Williams & Wilkins.

引用

页码：797 / 801

页数：5

共 16 条

[1] Stimulus-dependent correlated firing in directionally selective retinal ganglion cells [J].

Amthor, FR ;

Tootle, JS ;

Grzywacz, NM .

VISUAL NEUROSCIENCE, 2005, 22 (06) :769-787

[2] The diverse functional roles and regulation of neuronal gap junctions in the retina [J].

Bloomfield, Stewart A. ;

Voelgyi, Bela .

NATURE REVIEWS NEUROSCIENCE, 2009, 10 (07) :495-506

[3] Mechanisms of concerted firing among retinal ganglion cells [J].

Brivanlou, IH ;

Warland, DK ;

Meister, M .

NEURON, 1998, 20 (03) :527-539

[4] Mosaic arrangement of ganglion cell receptive fields in rabbit retina [J].

DeVries, SH ;

Baylor, DA .

JOURNAL OF NEUROPHYSIOLOGY, 1997, 78 (04) :2048-2060

[5] Correlated firing in rabbit retinal ganglion cells [J].

DeVries, SH .

JOURNAL OF NEUROPHYSIOLOGY, 1999, 81 (02) :908-920

[6] Dendrodendritic electrical synapses between mammalian retinal ganglion cells [J].

Hidaka, S ;

Akahori, Y ;

Kurosawa, Y .

JOURNAL OF NEUROSCIENCE, 2004, 24 (46) :10553-10567

[7] Synchronized retinal oscillations encode essential information for escape behavior in frogs [J].

Ishikane, H ;

Gangi, M ;

Honda, S ;

Tachibana, M .

NATURE NEUROSCIENCE, 2005, 8 (08) :1087-1095

[8] Short- and long-range synchronous activities in dimming detectors of the frog retina [J].

Ishikane, H ;

Kawana, A ;

Tachibana, M .

VISUAL NEUROSCIENCE, 1999, 16 (06) :1001-1014

[9] WHAT THE FROGS EYE TELLS THE FROGS BRAIN [J].

LETTVIN, JY ;

MATURANA, HR ;

MCCULLOCH, WS ;

PITTS, WH .

PROCEEDINGS OF THE INSTITUTE OF RADIO ENGINEERS, 1959, 47 (11) :1940-1951

[10] Contribution of the GABAergic pathway(s) to the correlated activities of chicken retinal ganglion cells [J].

Liu, Xue ;

Zhou, Yi ;

Gong, Hai-Qing ;

Liang, Pei-Ji .

BRAIN RESEARCH, 2007, 1177 :37-46

← 1 2 →