Why one task is not enough: Functional MRI for atypical language organization in two children

被引：18

作者：

Wilke, Marko ^{[1
,2
]}

Pieper, Tom ^{[3
]}

Lindner, Katja ^{[1
]}

Dushe, Thekla ^{[3
]}

Holthausen, Hans ^{[3
]}

Kraegeloh-Mann, Ingeborg ^{[1
]}

机构：

[1] Univ Tubingen, Childrens Hosp, Dept Pediat Neurol & Dev Med, D-72076 Tubingen, Germany

[2] Univ Tubingen, Dept Neuroradiol, CNS, Sect Expt MR, D-72076 Tubingen, Germany

[3] Behandlungszentrum Vogtareuth, Epilepsy Ctr Children & Adolescents, Specialist Ctr Pediat Neurol, Vogtareuth, Germany

来源：

EUROPEAN JOURNAL OF PAEDIATRIC NEUROLOGY | 2010年 / 14卷 / 06期

关键词：

Functional MRI; Epilepsy surgery; Dominant hemisphere; Wada test; HEMISPHERIC ORGANIZATION; SPEECH; FMRI; LATERALIZATION; PLASTICITY; DOMINANCE; EPILEPSY;

D O I：

10.1016/j.ejpn.2010.05.002

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Functional MRI is increasingly used to determine the hemispheric dominance for language. This is especially relevant in children who may not be able to comply with the high demands of a Wada test. We here report on two children in which the full extent of language reorganization was only determined when two fMRI tasks were analyzed; in the first case, the results from the second task corroborated the shifted hemispheric dominance seen in the first task. In the second case, the second task showed an opposite hemispheric dominance, suggesting a hemispheric dissociation of language functions. These cases underline the necessity to use more than one fMRI task for the determination of hemispheric dominance, whenever possible. This is particularly relevant in children as unusual patterns of reorganization may be more likely. (C) 2010 European Paediatric Neurology Society. Published by Elsevier Ltd. All rights reserved.

引用

页码：474 / 478

页数：5

共 19 条

[1] Bilateral and Independent Broca Areas Confirmed by Wada Test and Functional Magnetic Resonance Imaging [J].

Biega, Timothy J. ;

Levy, Lucien M. ;

Bannout, Firas ;

Gaillard, William D. ;

Potolicchio, Samuel J. .

JOURNAL OF COMPUTER ASSISTED TOMOGRAPHY, 2009, 33 (04) :560-561

[2] Imaging cognition II: An empirical review of 275 PET and fMRI studies [J].

Cabeza, R ;

Nyberg, L .

JOURNAL OF COGNITIVE NEUROSCIENCE, 2000, 12 (01) :1-47

[3] Dissociating speech perception and comprehension at reduced levels of awareness [J].

Davis, Matthew H. ;

Coleman, Martin R. ;

Absalom, Anthony R. ;

Rodd, Jennifer M. ;

Johnsrude, Ingrid S. ;

Matta, Basil F. ;

Owen, Adrian M. ;

Menon, David K. .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2007, 104 (41) :16032-16037

[4] Conjunction revisited [J].

Friston, KJ ;

Penny, WD ;

Glaser, DE .

NEUROIMAGE, 2005, 25 (03) :661-667

[5] fMRI language task panel improves determination of language dominance [J].

Gaillard, WD ;

Balsamo, L ;

Xu, B ;

McKinney, C ;

Papero, PH ;

Weinstein, S ;

Conry, J ;

Pearl, PL ;

Sachs, B ;

Sato, S ;

Vezina, LG ;

Frattali, C ;

Theodore, WH .

NEUROLOGY, 2004, 63 (08) :1403-1408

[6] Late plasticity for language in a child's non-dominant hemisphere -: A pre- and post-surgery fMRI study [J].

Hertz-Pannier, L ;

Chiron, C ;

Jambaqué, I ;

Renaux-Kieffer, V ;

Van de Moortele, PF ;

Delalande, O ;

Fohlen, M ;

Brunelle, F ;

Le Bihan, D .

BRAIN, 2002, 125 :361-372

[7] Opinion - The cortical organization of speech processing [J].

Hickok, Gregory ;

Poeppel, David .

NATURE REVIEWS NEUROSCIENCE, 2007, 8 (05) :393-402

[8] The spatial and temporal signatures of word production components [J].

Indefrey, P ;

Levelt, WJM .

COGNITION, 2004, 92 (1-2) :101-144

[9] Real-time functional MR imaging (fMRI) for presurgical evaluation of paediatric epilepsy [J].

Kesavadas, Chandrasekharan ;

Thomas, Bejoy ;

Sujesh, Sreedharan ;

Ashalata, Radhakrishnan ;

Abraham, Mathew ;

Gupta, Arun Kumar ;

Radhakrishnan, Kurupath .

PEDIATRIC RADIOLOGY, 2007, 37 (10) :964-974

[10] Limitations to plasticity of language network reorganization in localization related epilepsy [J].

Mbwana, J. ;

Berl, M. M. ;

Ritzl, E. K. ;

Rosenberger, L. ;

Mayo, J. ;

Weinstein, S. ;

Conry, J. A. ;

Pearl, P. L. ;

Shamim, S. ;

Moore, E. N. ;

Sato, S. ;

Vezina, L. G. ;

Theodore, W. H. ;

Gaillard, W. D. .

BRAIN, 2009, 132 :347-356

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