Micronutrient status in children with cerebral palsy

被引:45
作者
Hillesund, Elisabet
Skranes, Jon
Trygg, Kerstin Ulla
Bohmer, Thomas
机构
[1] Sorlandet Hosp, Dept Pediat, N-4809 Arendal, Norway
[2] Norwegian Univ Sci & Technol, Dept Lab Med, N-7034 Trondheim, Norway
[3] Univ Oslo, Dept Nutr, Oslo, Norway
[4] Aker Univ Hosp, Nutr Lab, Oslo, Norway
关键词
cerebral palsy; micronutrient deficiencies; nutrition assessment; tube feeding;
D O I
10.1111/j.1651-2227.2007.00354.x
中图分类号
R72 [儿科学];
学科分类号
100202 ;
摘要
Aim: To investigate micronutrient status in a group of children with cerebral palsy (CP). Methods: Thirty-six children with CP, aged 1.5-17 years, completed a 4-day food diary, underwent anthropometric measurements and delivered blood for analysis of micronutrient concentrations. Results: Low intake of iron, folate, niacin, calcium, vitamin E and vitamin D was common, even among those who were receiving nutritional supplements. Laboratory tests revealed low serum concentration of folate in eight children, alpha-tocopherol in six children, ferritin in five children and pyridoxal-5-phosphate in three children. Two participants were low in zinc and one was low in selenium. Severely disabled children received nutrition supplements more frequently than those with less severe disability (71% vs.16%, p = 0.01). Tube feeding and use of nutrition supplements was reflected in higher concentrations of micronutrients in blood and serum. Conclusion: Low intake of micronutrients as well as low micronutrient concentrations was common in this heterogenic group of children with CP. Children with neurological disabilities should have their nutritional status evaluated in order to ascertain sufficient intake of micronutrients.
引用
收藏
页码:1195 / 1198
页数:4
相关论文
共 19 条
  • [1] DNA damage from micronutrient deficiencies is likely to be a major cause of cancer
    Ames, BN
    [J]. MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS, 2001, 475 (1-2) : 7 - 20
  • [2] Energy expenditure and body composition in children with spastic quadriplegic cerebral palsy
    Azcue, MP
    Zello, GA
    Levy, LD
    Pencharz, PB
    [J]. JOURNAL OF PEDIATRICS, 1996, 129 (06) : 870 - 876
  • [3] Bingham S. A., 1987, Nutrition Abstracts and Reviews. Series A-Human and Experimental, V57, P705
  • [4] Dietary considerations in osteopenia in tube-fed nonambulatory children with cerebral palsy
    Duncan, B
    Barton, LL
    Lloyd, J
    Marks-Katz, M
    [J]. CLINICAL PEDIATRICS, 1999, 38 (03) : 133 - 137
  • [5] Studies on nutrition in severely neurologically disabled children in an institution
    Hals, J
    Ek, J
    Svalastog, AG
    Nilsen, H
    [J]. ACTA PAEDIATRICA, 1996, 85 (12) : 1469 - 1475
  • [6] Bone density and metabolism in children and adolescents with moderate to severe cerebral palsy
    Henderson, RC
    Lark, RK
    Gurka, MJ
    Worley, G
    Fung, EB
    Conaway, M
    Stallings, VA
    Stevenson, RD
    [J]. PEDIATRICS, 2002, 110 (01) : e5
  • [7] Multiple micronutrient deficiencies in a child fed an elemental formula
    Jones, M
    Campbell, KA
    Duggan, C
    Young, G
    Bousvaros, A
    Higgins, L
    Mullen, E
    [J]. JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION, 2001, 33 (05) : 602 - 605
  • [8] Pattern of growth in children with cerebral palsy
    Krick, J
    MurphyMiller, P
    Zeger, S
    Wright, E
    [J]. JOURNAL OF THE AMERICAN DIETETIC ASSOCIATION, 1996, 96 (07) : 680 - 685
  • [9] LONG-TERM DEVELOPMENTAL OUTCOME OF INFANTS WITH IRON-DEFICIENCY
    LOZOFF, B
    JIMENEZ, E
    WOLF, AW
    [J]. NEW ENGLAND JOURNAL OF MEDICINE, 1991, 325 (10) : 687 - 694
  • [10] Cobalamin status and its biochemical markers methylmalonic acid and homocysteine in different age groups from 4 days to 19 years
    Monsen, AUB
    Refsum, H
    Markestad, T
    Ueland, PM
    [J]. CLINICAL CHEMISTRY, 2003, 49 (12) : 2067 - 2075