Auricular acupuncture decreases neuropeptide Y expression in the hypothalamus of food-deprived Sprague-Dawley rats

被引：18
作者：
Kima, EH
Kima, YH
Jang, MH
Lim, BV
Kim, YJ
Chung, JH
Kim, CJ [1 ]
机构：
[1] Kyung Hee Univ, Coll Med, Dept Physiol, Seoul 130701, South Korea
[2] Kyung Hee Univ, Coll Med, Dept Pharmacol, Seoul 130701, South Korea
[3] Semyung Univ, Coll Oriented Med, Dept Meridianol, Chungbuk 390711, South Korea
来源：
NEUROSCIENCE LETTERS | 2001年 / 307卷 / 02期
关键词：
auricular acupuncture; immunohistochemistry; food intake; hypothalamus; neuropeptide Y; arcuate nucleus; paraventricular nucleus;
D O I：
10.1016/S0304-3940(01)01948-6
中图分类号：
Q189 [神经科学];
学科分类号：
071006 ;
摘要：
The aim of the present study was to investigate whether stimulation of auricular acupuncture point has any effects on the expression of neuropeptide Y (NPY), appetite-inducing factor particularly abundant in the mammalian hypothalamus. in food-deprived condition, enhanced NPY expression was detected in both the arcuate nucleus (ARN) and the paraventricular nucleus (PVN) of the hypothalamus via immunohistochemistry in Sprague-Dawley rats. Needling the unfed rats on the auricular point resulted in decreased NPY levels in both the ARN and PVN, while it increased NPY levels in the ARN and PVN of fed rats. The present findings indicate that auricular acupuncture may affect NPY expression in the ARN and PVN of the hypothalamus. (C) 2001 Elsevier Science Ireland Ltd. All rights reserved.
引用
收藏
页码：113 / 116
页数：4
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