NMR studies of the conformational behaviour and tautomerism of bis- and tris-saccharidoguanidines

被引：3

作者：

Tóth, G

Gáti, T

Pintér, I

Kovács, J

Haessner, R

机构：

[1] Budapest Univ Technol & Econ, Tech Analyt Res Grp, Hungarian Acad Sci, Inst Gen & Analyt Chem, H-1111 Budapest, Hungary

[2] PROCHEM Res & Dev Ltd, H-1525 Budapest, Hungary

[3] Tech Univ Munich, Inst Organ Chem, D-85747 Garching, Germany

来源：

MAGNETIC RESONANCE IN CHEMISTRY | 2001年 / 39卷 / 05期

关键词：

NMR; H-1; C-13; guanidino sugars; conformational analysis; tautomerism; ROESY; exchange;

D O I：

10.1002/mrc.835

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The reaction of an acetyl-protected symmetrical sugar carbodiimide with amines yielded the corresponding trisubstituted guanidine derivatives 2-6 with two or three sugar units. Their tautomerism, isomerism and conformational behaviour were elucidated by application of one- and two-dimensional H-1 and C-13 NMR spectroscopy. The rate of tautomerisation was calculated from ROESY exchange measurements. Copyright (C) 2001 John Wiley & Sons, Ltd.

引用

页码：283 / 287

页数：5

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