Protein misfolding and medicinal strategies in neurodegenerative disorders

被引：0

作者：

Mehboudi, Leila ^{[1
]}

Zahedirad, Mehrshad ^{[2
]}

Vadiei, Parisa ^{[2
]}

机构：

[1] Jahrom Univ Med Sci, Fac Med, Dept Anesthesia, Jahrom, Iran

[2] Islamic Azad Univ, Dept Med Lab, Chalus Branch, Fac Paramed Sci, Chalus, Iran

来源：

MEDICINA BALEAR | 2022年 / 37卷 / 04期

关键词：

Protein misfolding; Alzheimer's disease; Huntington's disease; Parkinson's disease; THERAPEUTIC STRATEGIES; DISEASES;

D O I：

10.3306/AJHS.2022.37.04.166

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Proteins that misfold may accumulate and cause disorders like Alzheimer's and Parkinson's. New medicines are also explored to forecast and even cure these illnesses' severe symptoms. Because they were misfolded during creation or maintenance, rogue proteins may harm a biological system. This causes over twenty human illnesses, including Alzheimer's, Huntington's, Parkinson's, and other neurodegenerative diseases. To create new therapies and medications, researchers will need to understand protein misfolding and aggregation formation. To summarize, protein misfolding causes aggregation and neurodegeneration. This suggests that nature employs protein aggregation to execute unique physiological activities in various biological conditions.

引用

页码：166 / 170

页数：5

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