Highly blood compatible titania gel

被引:22
作者
Takemoto, S
Tsuru, K
Hayakawa, S
Osaka, A
Takashima, S
机构
[1] Okayama Univ, Grad Sch Nat Sci & Technol, Okayama 7008530, Japan
[2] Okayama Univ, Fac Engn, Biomat Lab, Okayama 7008530, Japan
[3] Okayama Univ, Cooperat Res Ctr, Okayama 7011221, Japan
关键词
blood compatibility; titania gel; chemical treatment; heating;
D O I
10.1023/A:1011269802356
中图分类号
TQ174 [陶瓷工业]; TB3 [工程材料学];
学科分类号
0805 ; 080502 ;
摘要
We examined blood compatibility of titania gels prepared through a sol-gel processing or yielded on titanium substrates by treating with hydrogen peroxide or simple heating. The blood compatibility was evaluated in terms of blood clotting time and correlated to the crystalline phases, roughness, specific surface area, and wettability. The sol-gel derived titania gel heated above 200 degreesC had good blood compatibility. Ti substrate treated with hydrogen peroxide and subsequently heated at 550 degreesC showed the best blood compatibility among the Ti substrates with or without the chemical treatment and heat-treatment. The specimen consisted of rutile and anatase phases, and had hydrophilic surface.
引用
收藏
页码:97 / 104
页数:8
相关论文
共 7 条
[1]  
BAURSCHMIDT P, 1977, J BIOENG, V1, P261
[2]  
NAN HA, 1994, J BIOMATER APPL, V8, P404
[3]   SURFACE AND BLOOD-CONTACTING PROPERTIES OF ALKYLSILOXANE MONOLAYERS SUPPORTED ON SILICONE-RUBBER [J].
SILVER, JH ;
HERGENROTHER, RW ;
LIN, JC ;
LIM, F ;
LIN, HB ;
OKADA, T ;
CHAUDHURY, MK ;
COOPER, SL .
JOURNAL OF BIOMEDICAL MATERIALS RESEARCH, 1995, 29 (04) :535-548
[4]  
Sunny M C, 1991, J Biomater Appl, V6, P89, DOI 10.1177/088532829100600107
[5]  
Takashima S., 1999, BIOCERAMICS, V12, P551
[6]   TITANIUM WITH DIFFERENT OXIDES - IN-VITRO STUDIES OF PROTEIN ADSORPTION AND CONTACT ACTIVATION [J].
WALIVAARA, B ;
ARONSSON, BO ;
RODAHL, M ;
LAUSMAA, J ;
TENGVALL, P .
BIOMATERIALS, 1994, 15 (10) :827-834
[7]  
Walivaara Bengt, 1993, Clinical Materials, V12, P141, DOI 10.1016/0267-6605(93)90065-F