Local anesthetics

被引：36
作者：
Skidmore, RA
Patterson, JD
Tomsick, RS
机构：
[1] Department of Dermatology, University of North Carolina, Chapel Hill, NC
[2] Department of Dermatology, University of North Carolina, CB 7287, Chapel Hill, NC 27599, Thurston-Bowles Bld.
来源：
DERMATOLOGIC SURGERY | 1996年 / 22卷 / 06期
关键词：
D O I：
10.1111/j.1524-4725.1996.tb00366.x
中图分类号：
R75 [皮肤病学与性病学];
学科分类号：
100206 ;
摘要：
BACKGROUND. Dermatology is dependent upon the effects of local anesthetics for diagnostic and therapeutic interventions. A working knowledge of the drugs' actions and interactions is necessary for anyone aspiring to optimize the benefits derived from the use local anesthetic agents. OBJECTIVE. This article reviews nerve physiology, pharmacology, classification of local anesthetics, adverse reactions (toxic, drug, allergic), local anesthetic use in pregnancy, alternatives to the ''-caine'' anesthetics, methods for reducing the pain of infiltration, and new agents under development. CONCLUSION. Local anesthetics are safe and effective. With the understanding of the actions and interactions of this class of drugs, maximum patient safety and satisfaction can be achieved.
引用
收藏
页码：511 / 522
页数：12
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