ULTRASOUND AND CONTRAST-ENHANCED ULTRASOUND FINDINGS AFTER PERCUTANEOUS IRREVERSIBLE ELECTROPORATION OF HEPATIC MALIGNANT TUMORS

被引:4
作者
Chai, Weilu [1 ,2 ]
Xie, Liting [1 ]
Zhao, Qiyu [1 ,2 ]
Cheng, Chao [2 ]
Tian, Guo [3 ]
Jiang, Tian'an [1 ,2 ]
Wu, Pingping [4 ]
机构
[1] Zhejiang Univ, Coll Med, Affiliated Hosp 1, Dept Ultrasonog, Hangzhou, Zhejiang, Peoples R China
[2] Zhejiang Univ, Coll Med, Affiliated Hosp 1, Dept Hepatobiliary & Pancreat Surg, Hangzhou, Zhejiang, Peoples R China
[3] Zhejiang Univ, Coll Med, Affiliated Hosp 1, Collaborat Innovat Ctr Diag & Treatment Infect Di, Hangzhou, Zhejiang, Peoples R China
[4] Zhejiang Univ, Affiliated Hosp 1, Coll Med, Liver Transplant Ctr, Hangzhou, Zhejiang, Peoples R China
关键词
Ultrasound; Radiographic image enhancement; Electroporation; Liver cancer; Malignancy; ASSESS IMMEDIATE RESPONSE; ADVANCED HEPATOCELLULAR-CARCINOMA; LIVER-TUMORS; ABLATION; CEUS; IRE; EFFICACY; SAFETY; US; CT;
D O I
10.1016/j.ultrasmedbio.2019.12.012
中图分类号
O42 [声学];
学科分类号
070206 ; 082403 ;
摘要
The aim of this study was to describe ultrasound (US) and contrast-enhanced ultrasound (CEUS) findings immediately and 1 d after percutaneous irreversible electroporation (IRE) of hepatic malignant tumors Immediately after IRE, the ablation zone was shown to be a gradually expanding hypo-echoic area around the electrodes. The microcirculation of the ablation zone was markedly reduced on CEUS (before vs. immediately after, p < 0.001), and the macrocirculation within the ablation zone was preserved. At 1 d after IRE, the ablation zones lost their hypoechogenicity to become iso-echoic or hyper-echoic (before vs. 1 d after, p= 0.004; immediately after vs. 1 d after, p = 0.002). At this time, further elimination of microcirculation was confirmed on CEUS (before vs. 1 d after, p < 0.001; immediately after vs. 1 d after, p = 0.003). The size of the ablation zone, which measured by US, was strongly correlated with that measured by CEUS (length: r: = 0.929, width: r = 0.940. p < 0.001), was significantly enlarged immediately after IRE and shrunk 1 d after IRE. (C) 2019 World Federation for Ultrasound in Medicine & Biology. All rights reserved.
引用
收藏
页码:620 / 629
页数:10
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