PM10 and pregnancy outcomes:: A hospital-based cohort study of pregnant women Seoul

被引:81
作者
Kim, Ok-Jin [1 ]
Ha, Eun-Hee [2 ]
Kim, Byung-Mi [2 ]
Seo, Ju-Hee [2 ]
Park, Hye-Sook [2 ]
Jung, Woo-Jae
Lee, Bo-Eun [3 ]
Suh, Young-Ju [2 ,3 ]
Kim, Young-Ju [4 ]
Lee, Jong-Tae [5 ,6 ]
Kim, Ho [1 ]
Hong, Yun-Chul [2 ]
机构
[1] Seoul Natl Univ, Sch Publ Hlth, Dept Epidemiol & Biostat, Seoul, South Korea
[2] Ewha Womans Univ, Coll Med, Dept Prevent Med, Ewha Med Res Ctr,Sch Med, Seoul 158056, South Korea
[3] Korea Ctr Dis Control & Prevent, Ewha Global Gchallenge Project Med, Div Cron Dis Surveillance, Seoul, South Korea
[4] Ewha Womans Univ, Sch Med, Dept Obstet & Gynecol, Seoul, South Korea
[5] Hanyang Univ, Dept Publ Hlth & Management, Seoul, South Korea
[6] Hanyang Univ, Inst Environm & Ind Med, Seoul, South Korea
关键词
D O I
10.1097/JOM.0b013e3181594859
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
Objective: The aim of this study was to evaluate the effects of PM10 on birth outcomes using a prospective cohort of pregnant women. Methods: The multicenter prospective study was conducted in Korea from 2001 to 2004. To estimate the effects of PM10 exposure on birth outcomes, the logistic and linear regression model and the generalized additive model for nonlinear relationships were used. Results: Stillbirths were affected by PM,, level during the third trimesters (OR = 1.10, 95% CI = 1.02-1.14), and birth defects were influenced by the PM10 exposure during the second trimesters (OR = 1.16, 95% CI = 1.00-1.34). Intrauterine growth retardation was affected by the first trimester's PM10 exposure. On the other hand, premature birth was affected by the PM10 exposure during the third trimester, and low-birth-weight births were affected by the PM10 level during entire trimesters of pregnancy. Conclusions: PM10 exposure during pregnancy may result in adverse birth outcomes with different critical periods.
引用
收藏
页码:1394 / 1402
页数:9
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