Traumatic brain injury

被引:142
作者
Risdall, Jane E. [1 ]
Menon, David K. [1 ]
机构
[1] Univ Cambridge, Div Anaesthesia, Cambridge CB2 2QQ, England
基金
英国医学研究理事会;
关键词
military; traumatic brain injury; blast injury; polytrauma triad; post-traumatic epilepsy; vasospasm; PERSISTENT POSTCONCUSSIVE SYMPTOMS; POSTTRAUMATIC-STRESS-DISORDER; CENTRAL-NERVOUS-SYSTEM; CLOSED-HEAD INJURY; INTRACRANIAL-PRESSURE; NONINVASIVE ASSESSMENT; INDUCED NEUROTRAUMA; COMBAT CASUALTIES; BOMB EXPLOSIONS; CHRONIC PAIN;
D O I
10.1098/rstb.2010.0230
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
There is an increasing incidence of military traumatic brain injury (TBI), and similar injuries are seen in civilians in war zones or terrorist incidents. Indeed, blast-induced mild TBI has been referred to as the signature injury of the conflicts in Iraq and Afghanistan. Assessment involves schemes that are common in civilcian practice but, in common with civilian TBI, takes little account of information available from modern imaging (particularly diffusion tensor magnetic resonance imaging) and emerging biomarkers. The efficient logistics of clinical care delivery in the field may have a role in optimizing outcome. Clinical care has much in common with civilian TBI, but intracranial pressure monitoring is not always available, and protocols need to be modified to take account of this. In addition, severe early oedema has led to increasing use of decompressive craniectomy, and blast TBI may be associated with a higher incidence of vasospasm and pseudoaneurysm formation. Visual and/or auditory deficits are common, and there is a significant risk of post-traumatic epilepsy. TBI is rarely an isolated finding in this setting, and persistent post-concussive symptoms are commonly associated with post-traumatic stress disorder and chronic pain, a constellation of findings that has been called the polytrauma clinical triad.
引用
收藏
页码:241 / 250
页数:10
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