Synthesis of (+)-altholactone, (+)-7-epi-altholactone, (-)-etharvensin, and (+)-alumheptolide-A using Pd-catalyzed carbonylation

被引：6

作者：

Miyazawa, Yuki ^{[1
]}

Hattori, Yasunao ^{[2
]}

Makabe, Hidefumi ^{[1
]}

机构：

[1] Shinshu Univ, Grad Sch Sci & Technol, Dept Agr, Div Food Sci & Biotechnol, 8304 Minami Minowa, Nagano 3994598, Japan

[2] Kyoto Pharmaceut Univ, Ctr Instrumental Anal, Yamashina Ku, Kyoto 6078412, Japan

来源：

TETRAHEDRON LETTERS | 2018年 / 59卷 / 45期

关键词：

Natural product; Polyketides; Styryl lactone; Carbonylation; ENANTIOSELECTIVE SYNTHESES; STYRYL-LACTONE; D-GLUCOSE; (+)-GONIOFUFURONE; (+)-GONIOPYPYRONE; ISOALTHOLACTONE; STYRYLLACTONES; (+)-GONIOTRIOL; SEMISYNTHESIS; CYTOTOXICITY;

D O I：

10.1016/j.tetlet.2018.09.062

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Syntheses of (+)-altholactone isolated from Goniothalamus giganteus and its C-7 epimer (+)-7-epi-altholactone, (-)-etharvensin and (+)-alumheptolide-A were achieved. The lactone ring of these compounds was constructed using Pd-catalyzed carbonylation. (C) 2018 Elsevier Ltd. All rights reserved.

引用

页码：4024 / 4027

页数：4

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