Synthetic aperture focusing technique for photoacoustic endoscopy

被引：38
作者：
Cai, De [1 ]
Li, Guangyao [1 ]
Xia, Dongqing [1 ]
Li, Zhongfei [1 ]
Guo, Zhendong [1 ]
Chen, Sung-Liang [1 ,2 ]
机构：
[1] Shanghai Jiao Tong Univ, Univ Michigan Shanghai Jiao Tong Univ Joint Inst, Shanghai 200240, Peoples R China
[2] Shanghai Jiao Tong Univ, State Key Lab Adv Opt Commun Syst & Networks, Shanghai 200240, Peoples R China
来源：
OPTICS EXPRESS | 2017年 / 25卷 / 17期
基金：
中国国家自然科学基金; 国家高技术研究发展计划(863计划);
关键词：
IN-VIVO; ULTRASONIC ENDOSCOPY; CATHETER; DETECTOR; PROBE;
D O I：
10.1364/OE.25.020162
中图分类号：
O43 [光学];
学科分类号：
070207 ; 0803 ;
摘要：
Photoacoustic endoscopy (PAE) is a promising tool for the detection of atherosclerotic plaque. In this work, we propose a novel design of a side-viewing PAE probe based on a synthetic aperture focusing technique (SAFT) to enable high transverse resolution over large depth of focus (DOF) along the radial direction. A point-like ultrasonic detector is used to ensure a wide detection angle and thus a large synthetic aperture for SAFT. We first perform numerical simulation to optimize the PAE probe design, which involves the placement of the point-like detector and the diameter of a reflection rod mirror. Then, experiments are conducted based on the optimized probe design. High transverse resolution of 115-190 mu m over large DOF of 3.5 mm along the radial direction is experimentally obtained. The SAFT-based PAE holds promise for endoscopic imaging with a high transverse resolution for both the surface and deep regions of tissue. (C) 2017 Optical Society of America
引用
收藏
页码：20162 / 20171
页数：10
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