Synthetic aperture focusing technique for photoacoustic endoscopy

被引:38
作者
Cai, De [1 ]
Li, Guangyao [1 ]
Xia, Dongqing [1 ]
Li, Zhongfei [1 ]
Guo, Zhendong [1 ]
Chen, Sung-Liang [1 ,2 ]
机构
[1] Shanghai Jiao Tong Univ, Univ Michigan Shanghai Jiao Tong Univ Joint Inst, Shanghai 200240, Peoples R China
[2] Shanghai Jiao Tong Univ, State Key Lab Adv Opt Commun Syst & Networks, Shanghai 200240, Peoples R China
基金
中国国家自然科学基金; 国家高技术研究发展计划(863计划);
关键词
IN-VIVO; ULTRASONIC ENDOSCOPY; CATHETER; DETECTOR; PROBE;
D O I
10.1364/OE.25.020162
中图分类号
O43 [光学];
学科分类号
070207 ; 0803 ;
摘要
Photoacoustic endoscopy (PAE) is a promising tool for the detection of atherosclerotic plaque. In this work, we propose a novel design of a side-viewing PAE probe based on a synthetic aperture focusing technique (SAFT) to enable high transverse resolution over large depth of focus (DOF) along the radial direction. A point-like ultrasonic detector is used to ensure a wide detection angle and thus a large synthetic aperture for SAFT. We first perform numerical simulation to optimize the PAE probe design, which involves the placement of the point-like detector and the diameter of a reflection rod mirror. Then, experiments are conducted based on the optimized probe design. High transverse resolution of 115-190 mu m over large DOF of 3.5 mm along the radial direction is experimentally obtained. The SAFT-based PAE holds promise for endoscopic imaging with a high transverse resolution for both the surface and deep regions of tissue. (C) 2017 Optical Society of America
引用
收藏
页码:20162 / 20171
页数:10
相关论文
共 29 条
[1]  
Allen T. J., 2015, P SOC PHOTO-OPT INS, V93230
[2]   Synthetic Aperture Focusing for a Single-Element Transducer Undergoing Helical Motion [J].
Andresen, Henrik ;
Nikolov, Svetoslav Ivanov ;
Jensen, Jorgen Arendt .
IEEE TRANSACTIONS ON ULTRASONICS FERROELECTRICS AND FREQUENCY CONTROL, 2011, 58 (05) :935-943
[3]   Intravascular Optical-Resolution Photoacoustic Tomography with a 1.1 mm Diameter Catheter [J].
Bai, Xiaosong ;
Gong, Xiaojing ;
Hau, William ;
Lin, Riqiang ;
Zheng, Jiaxiang ;
Liu, Chengbo ;
Zeng, Chengzhi ;
Zou, Xin ;
Zheng, Hairong ;
Song, Liang .
PLOS ONE, 2014, 9 (03)
[4]  
Blackstock D., 2000, Fundamentals of physical acoustics
[5]   Photoacoustic microscopy by scanning mirror-based synthetic aperture focusing technique [J].
Cai, De ;
Li, Zhongfei ;
Chen, Sung-Liang .
CHINESE OPTICS LETTERS, 2015, 13 (10)
[6]   Development of a 35-MHz piezo-composite ultrasound array for medical imaging [J].
Cannata, JM ;
Williams, JA ;
Zhou, QF ;
Ritter, TA ;
Shung, KK .
IEEE TRANSACTIONS ON ULTRASONICS FERROELECTRICS AND FREQUENCY CONTROL, 2006, 53 (01) :224-236
[7]   Mechanical characterization of intraluminal tissue with phase-resolved photoacoustic viscoelasticity endoscopy [J].
Chen, Conggui ;
Zhao, Yue ;
Yang, Sihua ;
Xing, Da .
BIOMEDICAL OPTICS EXPRESS, 2015, 6 (12) :4975-4980
[8]   Low-noise small-size microring ultrasonic detectors for high-resolution photoacoustic imaging [J].
Chen, Sung-Liang ;
Ling, Tao ;
Guo, L. Jay .
JOURNAL OF BIOMEDICAL OPTICS, 2011, 16 (05)
[9]   Synthetic aperture focusing for medical endoscopic ultrasonography [J].
Chen, Xiaodong ;
Li, Ming ;
Li, Yan ;
Wang, Yi ;
Yu, Daoyin .
JOURNAL OF X-RAY SCIENCE AND TECHNOLOGY, 2011, 19 (01) :127-137
[10]   PHOTOACOUSTIC MONOPOLE RADIATION IN 1-DIMENSION, 2-DIMENSION, AND 3-DIMENSION [J].
DIEBOLD, GJ ;
SUN, T ;
KHAN, MI .
PHYSICAL REVIEW LETTERS, 1991, 67 (24) :3384-3387