Characterization of a novel allele HLA-B*3549

被引:2
作者
Chang, Y
Desai, L
Fan, TX
Santana, Z
Day, NK
机构
[1] Univ S Florida, All Childrens Hosp, HLA Lab, Dept 7050, St Petersburg, FL 33701 USA
[2] Univ S Florida, Coll Med, Dept Pediat, St Petersburg, FL 33701 USA
[3] Univ S Florida, All Childrens Hosp, Immunoparameters Lab, St Petersburg, FL 33701 USA
来源
TISSUE ANTIGENS | 2005年 / 65卷 / 02期
关键词
HLA-B*3549; PCR-SSP; SBT;
D O I
10.1111/j.1399-0039.2005.00346.x
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
A novel HLA-B allele, B*3549, was identified in a bone marrow transplantation candidate. B*3549 differs from B*3525 by two nucleotides at exon 2, position 142 (T to G) and 165 (G to C). The difference at position 142 resulted in an amino acid difference (serine to alanine). However, the difference at position 165 did not cause any amino acid change. This novel allele was found on a haplotype with A*3101, B*3549, Cw*0401, DRB1*0407, and DQB1*0302.
引用
收藏
页码:192 / 194
页数:3
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