The Effect of Community-Based Support Services on Clinical Efficacy and Health-Related Quality of Life in HIV/AIDS Patients in Resource-Limited Settings in Sub-Saharan Africa

被引：51

作者：

Kabore, Inoussa ^{[1
]}

Bloem, Jeanette ^{[1
]}

Etheredge, Gina ^{[1
]}

Obiero, Walter ^{[1
]}

Wanless, Sebastian ^{[2
]}

Doykos, Patricia ^{[3
]}

Ntsekhe, Pearl ^{[4
]}

Mtshali, Nomantshali ^{[5
]}

Afrikaner, Eric

Sayed, Rauf ^{[6
]}

Bostwelelo, John

Hani, Andiswa

Moshabesha, Tiisetso

Kalaka, Agnes

Mameja, Jerry

Zwane, Nompumelelo

Shongwe, Nomvuyo

Mtshali, Phangisile ^{[7
]}

Mohr, Beryl ^{[7
]}

Smuts, Archie ^{[7
]}

Tiam, Appolinaire ^{[4
]}

机构：

[1] Family Hlth Int, Arlington, VA 22031 USA

[2] Baylor Coll Med, Houston, TX 77030 USA

[3] BMSF, New York, NY USA

[4] Senkatana Ctr, Maseru, Lesotho

[5] Mpilohnle Project, Ladysmith, Kwa Zulu Natal, South Africa

[6] Sch Publ Hlth & Family Med, Cape Town, South Africa

[7] BMSF, Bedfordview, Gauteng, South Africa

来源：

AIDS PATIENT CARE AND STDS | 2010年 / 24卷 / 09期

关键词：

ACTIVE ANTIRETROVIRAL THERAPY; HIV-INFECTED ADULTS; RAPID SCALE-UP; POOR SETTINGS; DRUG-RESISTANCE; ADHERENCE; BARRIERS; PROGRAM; PREDICTORS; CHALLENGES;

D O I：

10.1089/apc.2009.0307

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

Antiretroviral therapy (ART) for HIV/AIDS in developing countries has been rapidly scaled up through directed public and private resources. Data on the efficacy of ART in developing countries are limited, as are operational research studies to determine the effect of selected nonmedical supportive care services on health outcomes in patients receiving ART. We report here on an investigation of the delivery of medical care combined with community-based supportive services for patients with HIV/AIDS in four resource-limited settings in sub-Saharan Africa, carried out between 2005 and 2007. The clinical and health-related quality of life (HRQOL) efficacy of ART combined with community support services was studied in a cohort of 377 HIV-infected patients followed for 18 months, in community-based clinics through patient interviews, clinical evaluations, and questionnaires. Patients exposed to community-based supportive services experienced a more rapid and greater overall increase in CD4 cell counts than unexposed patients. They also had higher levels of adherence, attributed primarily to exposure to home-based care services. In addition, patients receiving home-based care and/or food support services showed greater improvements in selected health-related QOL indicators. This report discusses the feasibility of effective ART in a large number of patients in resource-limited settings and the added value of concomitant community-based supportive care services.

引用

页码：581 / 594

页数：14

共 40 条

[11] Scaling up of highly active antiretroviral therapy in a rural district of Malawi: an effectiveness assessment [J].