Validation of a graphic measurement of heart rate variability to assess analgesia/nociception balance during general anesthesia

被引:92
作者
Jeanne, M. [1 ,2 ]
Logier, R. [2 ]
De Jonckheere, J. [2 ]
Tavernier, B. [1 ]
机构
[1] Univ Hosp Lille, Clin Anesthesie Reanimat, Hop Salengro, 2 Ave Oscar Lambret, F-59037 Lille, France
[2] Univ Hosp Lille, Biosensors & E Health, INSERM CIC IT, F-59037 Lille, France
来源
2009 ANNUAL INTERNATIONAL CONFERENCE OF THE IEEE ENGINEERING IN MEDICINE AND BIOLOGY SOCIETY, VOLS 1-20 | 2009年
关键词
Analgesia Monitoring; Pain Evaluation; Heart Rate Variability;
D O I
10.1109/IEMBS.2009.5332598
中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
The optimization of analgesic drugs delivery during general anesthesia (GA) requires to evaluate the pain/analgesia balance. Heart Rate Variability (HRV) analysis has long been shown to measure the autonomic nervous system tone, which is strongly influenced by anesthetic drugs. Power spectrum measurements are widely used to assess HRV low (LF) and high frequency (HF) ranges, related to the sympathetic and parasympathetic systems. We have developed an original graphic measurement technique (EnvTOT) of the ventilatory influence on the RR series. Measurements on simulated RR series showed that the graphic assessment is independent from respiratory rate, while LF and HF spectral measurements are over- and underestimated for respiratory rates lower than 12 cycles mind. Clinical measurements on 49 patients during GA showed that normalized HF power was strongly related to hemodynamic responsiveness during GA, and was strongly correlated with normalized EnvTOT measurements. A real time computation of the RR series could therefore help medical staff to anticipate hemodynamic responsiveness and the analgesia/nociception balance during GA.
引用
收藏
页码:1840 / +
页数:2
相关论文
共 7 条
[1]  
Camm AJ, 1996, CIRCULATION, V93, P1043
[2]  
JEANNE M, 2009, AUTON NEUROSCI 0207
[3]   EFFECTS OF SURGICAL STIMULATION ON AUTONOMIC REFLEX FUNCTION - ASSESSMENT BY CHANGES IN HEART-RATE-VARIABILITY [J].
LATSON, TW ;
OFLAHERTY, D .
BRITISH JOURNAL OF ANAESTHESIA, 1993, 70 (03) :301-305
[4]  
Logier R, 2006, 2006 28TH ANNUAL INTERNATIONAL CONFERENCE OF THE IEEE ENGINEERING IN MEDICINE AND BIOLOGY SOCIETY, VOLS 1-15, P3600
[5]  
Logier R., 1993, Conference Proceedings. 1993 International Conference on Systems, Man and Cybernetics. Systems Engineering in the Service of Humans (Cat. No.93CH3242-5), P172, DOI 10.1109/ICSMC.1993.385005
[6]  
Logier R., 2004, Method and device for assessing pain in human being-European patent, Patent No. [04370029.3, 043700293]
[7]   Wavelet transform to quantify heart rate variability and to assess its instantaneous changes [J].
Pichot, V ;
Gaspoz, JM ;
Molliex, S ;
Antoniadis, A ;
Busso, T ;
Roche, F ;
Costes, F ;
Quintin, L ;
Lacour, JR ;
Barthélémy, JC .
JOURNAL OF APPLIED PHYSIOLOGY, 1999, 86 (03) :1081-1091