Gene therapy to keep the QT rhythms "on the QT''

被引:2
作者
Agrawal, Devendra K. [1 ]
Boosani, Chandra S. [1 ]
机构
[1] Creighton Univ, Sch Med, Dept Clin & Translat Sci, CRISS 2 Room 510,2500 Calif Plaza, Omaha, NE 68178 USA
基金
美国国家卫生研究院;
关键词
I-KR;
D O I
10.1016/j.jtcvs.2017.07.005
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
引用
收藏
页码:1641 / 1643
页数:3
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共 10 条
[1]   Cellular reprogramming in cardiac diseases: A feather in the hat of regenerative medicine [J].
Agrawal, Devendra K. ;
Boosani, Chandra S. .
JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY, 2017, 153 (02) :327-328
[2]   Selective Molecular Potassium Channel Blockade Prevents Atrial Fibrillation [J].
Amit, Guy ;
Kikuchi, Kan ;
Greener, Ian D. ;
Yang, Lizhu ;
Novack, Victor ;
Donahue, J. Kevin .
CIRCULATION, 2010, 121 (21) :2263-2270
[3]   Direct Reprogramming of Fibroblasts into Functional Cardiomyocytes by Defined Factors [J].
Ieda, Masaki ;
Fu, Ji-Dong ;
Delgado-Olguin, Paul ;
Vedantham, Vasanth ;
Hayashi, Yohei ;
Bruneau, Benoit G. ;
Srivastava, Deepak .
CELL, 2010, 142 (03) :375-386
[4]   Labetalol, nebivolol, and propranolol relax human radial artery used as coronary bypass graft [J].
Korkmaz, Ozge ;
Sarac, Bulent ;
Goksel, Sabahattin ;
Yildirim, Sahin ;
Berkan, Ocal ;
Bagcivan, Ihsan .
JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY, 2015, 149 (04) :1036-1040
[5]   Preclinical efficacy and safety of KCNH2-G628S gene therapy for postoperative atrial fibrillation [J].
Liu, Zhao ;
Hutt, Julie A. ;
Rajeshkumar, Barur ;
Azuma, Yoshihiro ;
Duan, Kailai L. ;
Donahue, J. Kevin .
JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY, 2017, 154 (05) :1644-+
[6]   In vitro experimental models for the risk assessment of antibiotic-induced QT prolongation (vol 553, pg 229, 2007) [J].
Lu, Hua Rong ;
Vlarninckx, Eddy ;
Van de Water, Andre ;
Rohrbacher, Jutta ;
Hennans, An ;
Gallacher, David J. .
EUROPEAN JOURNAL OF PHARMACOLOGY, 2007, 577 (1-3) :221-232
[7]   In situ reprogramming to transdifferentiate fibroblasts into cardiomyocytes using adenoviral vectors: Implications for clinical myocardial regeneration [J].
Mathison, Megumi ;
Singh, Vivek P. ;
Chiuchiolo, Maria J. ;
Sanagasetti, Deepthi ;
Mao, Yun ;
Patel, Vivekkumar B. ;
Yang, Jianchang ;
Kaminsky, Stephen M. ;
Crystal, Ronald G. ;
Rosengart, Todd K. .
JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY, 2017, 153 (02) :329-+
[8]   Specific serine proteases selectively damage KCNH2 (hERG1) potassium channels and IKr [J].
Rajamani, S ;
Anderson, CL ;
Valdivia, CR ;
Eckhardt, LL ;
Foell, JD ;
Robertson, GA ;
Kamp, TJ ;
Makielski, JC ;
Anson, BD ;
January, CT .
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY, 2006, 290 (03) :H1278-H1288
[9]   Molecular ablation of ventricular tachycardia after myocardial infarction [J].
Sasano, Tetsuo ;
McDonald, Amy D. ;
Kikuchi, Kan ;
Donahue, J. Kevin .
NATURE MEDICINE, 2006, 12 (11) :1256-1258
[10]   Screening for Acute IKr Block Is Insufficient to Detect Torsades de Pointes Liability Role of Late Sodium Current [J].
Yang, Tao ;
Chun, Young Wook ;
Stroud, Dina M. ;
Mosley, Jonathan D. ;
Knollmann, Bjorn C. ;
Hong, Charles ;
Roden, Dan M. .
CIRCULATION, 2014, 130 (03) :224-U50