Applying the brakes on gene expression

被引：1
|
作者：
Mühlemann, O [1 ]
机构：
[1] Univ Bern, Inst Cell Biol, Bern, Switzerland
来源：
NATURE STRUCTURAL & MOLECULAR BIOLOGY | 2005年 / 12卷 / 12期
关键词：
D O I：
10.1038/nsmb1205-1024
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Eukaryotic messenger RNAs are degraded through a pathway that starts with the removal of the poly(A) tail. A recent study shows that cytoplasmic mRNA deadenylation in mammals occurs by the consecutive action of two distinct deadenylases and that degradation of nonsense mRNA involves the same biphasic deadenylation pathway.
引用
收藏
页码：1024 / 1025
页数：2
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