KF/Al2O3-Mediated Michael addition of thiols to electron-deficient olefins

被引：23

作者：

Moghaddam, FM ^{[1
]}

Bardajee, GR ^{[1
]}

Veranlou, ROC ^{[1
]}

机构：

[1] Sharif Univ Technol, Dept Chem, Tehran, Iran

来源：

SYNTHETIC COMMUNICATIONS | 2005年 / 35卷 / 18期

关键词：

electron-deficient olefins; KF/Al2O3; Michael addition; thiols;

D O I：

10.1080/00397910500189783

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Potassium fluoride supported on alumina efficiently catalyzes Michael addition of aromatic and aliphatic thiols to a variety of conjugated alkenes such as alpha,beta-unsaturated carbonyl compounds, carboxylic esters, amides, nitriles and chalcones. The Michael adducts are produced in good to excellent yields and relatively in short times. The catalyst can be recycled for subsequent reactions without any appreciable loss of efficiency.

引用

页码：2427 / 2433

页数：7

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