Koi herpesvirus (KHV) and KHV disease (KHVD) - a recently updated overview

被引：35

作者：

Bergmann, S. M. ^{[1
]}

Jin, Y. ^{[1
]}

Franzke, K. ^{[1
]}

Grunow, B. ^{[2
]}

Wang, Q. ^{[3
]}

Klafack, S. ^{[1
,4
]}

机构：

[1] Friedrich Loeffler Inst, Inst Infectol, OIE & Natl Reference Lab KHVD, Sudufer 10, D-17493 Greifswald, Germany

[2] Leibniz Inst Farm Anim Biol FBN, Inst Muscle Biol & Growth, Jr Res Grp Fish Growth Physiol, Dummerstorf, Germany

[3] Chinese Acad Fishery Sci, Peal River Fisheries Res Inst, Key Lab Aquat Anim Immune Technol, Key Lab Fishery Drug Dev,Minist Agr, Guangzhou, Peoples R China

[4] Ernst Moritz Arndt Univ Greifswald, Inst Med Biochem & Mol Biol, Greifswald, Germany

来源：

JOURNAL OF APPLIED MICROBIOLOGY | 2020年 / 129卷 / 01期

关键词：

aquaculture; diseases; fish (live); genetic; KHV; KHVD; viruses; CYPRINUS-CARPIO-KOI; VIRAL DISEASE; COMMON CARP; VIRUS; GENOME; SUSCEPTIBILITY; IDENTIFICATION; INFECTION; GOLDFISH; HYBRIDS;

D O I：

10.1111/jam.14616

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Over the last years, there has been an enormous increase in the knowledge on koi herpesvirus (KHV), koi herpesvirus disease (KHVD), pathogenesis and virus variants. Different KHV lineages have clearly been identified, possible genomic changes during replication in different cell cultures at different temperatures but also in several hosts have been identified, a persistent stage of infection has been specified and it has been shown that infection with KHV is not host specific at all, but KHVD is. Additionally, it has been shown that it is possible to combat KHVD by immunization with inactivated and attenuated live vaccines using different delivery systems but also to benefit from alternative treatments with e.g. exopolysaccharids obtained fromArthrospira platensis.

引用

页码：98 / 103

页数：6

共 42 条

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