ATP synthase - A marvellous rotary engine of the cell

被引：727
作者：
Yoshida, M [1 ]
Muneyuki, E [1 ]
Hisabori, T [1 ]
机构：
[1] Tokyo Inst Technol, Chem Resources Lab, Yokohama, Kanagawa 2268503, Japan
来源：
NATURE REVIEWS MOLECULAR CELL BIOLOGY | 2001年 / 2卷 / 09期
关键词：
D O I：
10.1038/35089509
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
ATP synthase can be thought of as a complex of two motors - the ATP-driven Ft motor and the proton-driven F-o motor - that rotate in opposite directions. The mechanisms by which rotation and catalysis are coupled in the working enzyme are now being unravelled on a molecular scale.
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收藏
页码：669 / 677
页数：9
相关论文
共 77 条
  • [61] Bacterial Na+-ATP synthase has an undecameric rotor
    Stahlberg, H
    Müller, DJ
    Suda, K
    Fotiadis, D
    Engel, A
    Meier, T
    Matthey, U
    Dimroth, P
    [J]. EMBO REPORTS, 2001, 2 (03) : 229 - 233
  • [62] Molecular architecture of the rotary motor in ATP synthase
    Stock, D
    Leslie, AGW
    Walker, JE
    [J]. SCIENCE, 1999, 286 (5445) : 1700 - 1705
  • [63] STRUCTURES OF METAL SITES OF OXIDIZED BOVINE HEART CYTOCHROME-C-OXIDASE AT 2.8 ANGSTROM
    TSUKIHARA, T
    AOYAMA, H
    YAMASHITA, E
    TOMIZAKI, T
    YAMAGUCHI, H
    SHINZAWAITOH, K
    NAKASHIMA, R
    YAONO, R
    YOSHIKAWA, S
    [J]. SCIENCE, 1995, 269 (5227) : 1069 - 1074
  • [64] Observations of rotation within the FOFl-ATP synthase:: deciding between rotation of the FOc subunit ring and artifact
    Tsunoda, SP
    Aggeler, R
    Noji, H
    Kinosita, K
    Yoshida, M
    Capaldi, RA
    [J]. FEBS LETTERS, 2000, 470 (03) : 244 - 248
  • [65] Cross-linking of two β subunits in the closed conformation in F1-ATPase
    Tsunoda, SP
    Muneyuki, E
    Amano, T
    Yoshida, M
    Noji, H
    [J]. JOURNAL OF BIOLOGICAL CHEMISTRY, 1999, 274 (09) : 5701 - 5706
  • [66] Large conformational changes of the ε subunit in the bacterial F1F0 ATP synthase provide a ratchet action to regulate this rotary motor enzyme
    Tsunoda, SP
    Rodgers, AJW
    Aggeler, R
    Wilce, MCJ
    Yoshida, M
    Capaldi, RA
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2001, 98 (12) : 6560 - 6564
  • [67] Rotation of the c subunit oligomer in fully functional F1Fo ATP synthase
    Tsunoda, SP
    Aggeler, R
    Yoshida, M
    Capaldi, RA
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2001, 98 (03) : 898 - 902
  • [68] Crystal structure of the epsilon subunit of the proton-translocating ATP synthase from Escherichia coli
    Uhlin, U
    Cox, GB
    Guss, JM
    [J]. STRUCTURE, 1997, 5 (09) : 1219 - 1230
  • [69] PRIMARY STRUCTURE AND SUBUNIT STOICHIOMETRY OF F1-ATPASE FROM BOVINE MITOCHONDRIA
    WALKER, JE
    FEARNLEY, IM
    GAY, NJ
    GIBSON, BW
    NORTHROP, FD
    POWELL, SJ
    RUNSWICK, MJ
    SARASTE, M
    TYBULEWICZ, VLJ
    [J]. JOURNAL OF MOLECULAR BIOLOGY, 1985, 184 (04) : 677 - 701
  • [70] WALKER JE, 1997, ATP SYNTHESIS ROTARY, P208
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