The Effects of Equine-assisted Activities and Therapy on Resting-state Brain Function in Attention-deficit/Hyperactivity Disorder: A Pilot Study

被引：25

作者：

Yoo, Jae Hyun ^{[1
,2
]}

Oh, Yunhye ^{[3
]}

Jang, Byongsu ^{[4
]}

Song, Jihye ^{[5
]}

Kim, Jiwon ^{[6
]}

Kim, Seonwoo ^{[6
]}

Lee, Jiyoung ^{[7
]}

Shin, Hye-Yeon ^{[7
]}

Kwon, Jeong-Yi ^{[8
]}

Kim, Yun-Hee ^{[8
]}

Jeong, Bumseok ^{[1
,2
]}

Joung, Yoo-Sook ^{[3
]}

机构：

[1] Korea Adv Inst Sci & Technol, Grad Sch Med Sci & Engn, Lab Clin Neurosci & Dev, 291 Daehak Ro, Daejeon 34141, South Korea

[2] Korea Adv Inst Sci & Technol, Inst Hlth Sci & Technol, Daejeon, South Korea

[3] Sungkyunkwan Univ, Sch Med, Samsung Med Ctr, Dept Psychiat, 81 Irwon Ro, Seoul 06351, South Korea

[4] Hae Sol Psychiat Clin, Dongtan, South Korea

[5] Hae Sol Psychiat Clin, Seoul, South Korea

[6] Samsung Biomed Res Inst, Seoul, South Korea

[7] Samsung Res & Dev Ctr, Samsung Equestrian Team, Gunpo, South Korea

[8] Sungkyunkwan Univ, Sch Med, Samsung Med Ctr, Dept Phys Med & Rehabil, Seoul, South Korea

来源：

CLINICAL PSYCHOPHARMACOLOGY AND NEUROSCIENCE | 2016年 / 14卷 / 04期

关键词：

Equine-assisted therapy; Regional homogeneity; Attention deficit hyperactivity disorder; Functional magnetic resonance imaging; Resting state; Default mode network; DEFICIT-HYPERACTIVITY DISORDER; DEFAULT NETWORK; CHILDREN; ADHD; INHIBITION; FMRI; METHYLPHENIDATE; DYSFUNCTION; RELEVANCE; PRECUNEUS;

D O I：

10.9758/cpn.2016.14.4.357

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Objective: Equine-assisted activities and therapy (EMIT) have been used as adjunct treatment options for physical and psychosocial rehabilitation. However, the therapeutic effects on resting state brain function have not yet been studied, The aim of this study is to investigate the effects of EAA/T on participants with attention-deficit/hyperactivity disorder (ADHD) by comparing resting state functional magnetic resonance imaging (rs-fMRI) signals and their clinical correlates. Methods: Ten participants with ADHD participated in a 12 week EAA/T program without any medication. Two rs-fMRls were acquired for all participants before and after EAA/T. For estimating therapeutic effect, the regional homogeneity (ReHo) method was applied to capture the changes in the regional synchronization of functional signals. Results: After the EAA/T program, clear symptom improvement was found even Without medication. Surface-based pairwise comparisons revealed that ReHo in the right precuneus and right pars orbitalis clusters had significantly diminished after the program. Reduced ReHo in the right precuneus cluster was positively correlated with changes in the scores on DuPaul's ADHD Rating Scale-Korean version. Conclusion: Our results indicate that EAA/T is associated with short-range functional connectivity in the regions related to the default mode network and the behavioral inhibition system, which are associated with symptom improvement.

引用

页码：357 / 364

页数：8

共 42 条

[1] Methylphenidate Normalizes Resting-State Brain Dysfunction in Boys With Attention Deficit Hyperactivity Disorder [J].