Screening newborns for primary T-cell immunodeficiencies: consensus and controversy

被引：0

作者：

Pedersen, Deborah J. Accetta ^{[1
,2
]}

Verbsky, James ^{[1
,2
,3
]}

Routes, John M. ^{[1
,2
,3
]}

机构：

[1] Med Coll Wisconsin, Dept Pediat, Milwaukee, WI 53226 USA

[2] Med Coll Wisconsin, Childrens Res Inst, Milwaukee, WI 53226 USA

[3] Med Coll Wisconsin, Dept Microbiol & Med Genet, Milwaukee, WI 53226 USA

来源：

EXPERT REVIEW OF CLINICAL IMMUNOLOGY | 2011年 / 7卷 / 06期

关键词：

hematopoietic stem cell transplantation; HSCT; NBS; newborn screening; SCID; severe combined immunodeficiency; T-cell lymphopenia; T-cell receptor excision circles; TREC; GENE-THERAPY; HOSPITAL VOLUME; THYMIC OUTPUT; MORTALITY; TRANSPLANTATION; PARENTS; ROTAVIRUS; INFANTS; IDENTIFICATION; CHILDREN;

D O I：

10.1586/ECI.11.25

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Newborn screening for early identification of T-cell lymphopenia and severe combined immunodeficiency has recently been recommended as an addition to the newborn screening programs in all states. This article will review the evidence supporting the use of this newborn screening test, and will outline the barriers to nationwide implementation, which include issues specific to this test and controversies regarding newborn screening in general.

引用

页码：761 / 768

页数：8

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