Cytokine storm in tuberculosis and IL-6 involvement

被引：37

作者：

Boni, Funmilayo Grace ^{[1
]}

Hamdi, Insaf ^{[1
]}

Koundi, Liadrine Moukendza ^{[1
]}

Shrestha, Kanchan ^{[1
]}

Xie, Jianping ^{[1
]}

机构：

[1] Southwest Univ, Inst Modern Biopharmaceut,Sch Life Sci,Minist Edu, State Key Lab Breeding Base Ecoenvironm & Bioress, Key Lab Ecoenvironm Three Gorges Reservoir Reserv, Chongqing 400700, Peoples R China

来源：

INFECTION GENETICS AND EVOLUTION | 2022年 / 97卷

关键词：

Tuberculosis; Cytokine storm; Immune response and IL-6; PULMONARY TUBERCULOSIS; CONTROLLED-TRIAL; LUNG-CANCER; INTERLEUKIN-6; PREDNISOLONE; RISK; TOCILIZUMAB; DIAGNOSIS; IBRUTINIB; IMMUNITY;

D O I：

10.1016/j.meegid.2021.105166

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

Tuberculosis is probably the most seasoned illness of the humanity. Intricacies or subsequent death emerging from these infections are frequently connected with cytokine storm. Interleukin-6 (IL-6) plays a crucial role in the immune response to tuberculosis. Therefore, there is a need to research some new therapeutic approaches to block IL-6 signaling that are right now being applied to the M. tuberculosis. In this review, we investigate the implication of IL-6 in the context of tuberculosis research.

引用

页数：6

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