Cytokine storm in tuberculosis and IL-6 involvement

被引：30
|
作者：
Boni, Funmilayo Grace [1 ]
Hamdi, Insaf [1 ]
Koundi, Liadrine Moukendza [1 ]
Shrestha, Kanchan [1 ]
Xie, Jianping [1 ]
机构：
[1] Southwest Univ, Inst Modern Biopharmaceut,Sch Life Sci,Minist Edu, State Key Lab Breeding Base Ecoenvironm & Bioress, Key Lab Ecoenvironm Three Gorges Reservoir Reserv, Chongqing 400700, Peoples R China
来源：
INFECTION GENETICS AND EVOLUTION | 2022年 / 97卷
关键词：
Tuberculosis; Cytokine storm; Immune response and IL-6; PULMONARY TUBERCULOSIS; CONTROLLED-TRIAL; LUNG-CANCER; INTERLEUKIN-6; PREDNISOLONE; RISK; TOCILIZUMAB; DIAGNOSIS; IBRUTINIB; IMMUNITY;
D O I：
10.1016/j.meegid.2021.105166
中图分类号：
R51 [传染病];
学科分类号：
100401 ;
摘要：
Tuberculosis is probably the most seasoned illness of the humanity. Intricacies or subsequent death emerging from these infections are frequently connected with cytokine storm. Interleukin-6 (IL-6) plays a crucial role in the immune response to tuberculosis. Therefore, there is a need to research some new therapeutic approaches to block IL-6 signaling that are right now being applied to the M. tuberculosis. In this review, we investigate the implication of IL-6 in the context of tuberculosis research.
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页数：6
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