Novel ferrocene-based inhibitor of proteins glycation

被引：4

作者：

Milaeva, E. R. ^{[1
,2
]}

Shpakovsky, D. B. ^{[1
]}

Meleshonkova, N. N. ^{[1
]}

Orlova, S. I. ^{[1
]}

Shevtsova, E. F. ^{[2
]}

Dubova, L. G. ^{[2
]}

Kireeva, E. G. ^{[2
]}

Kosolapov, V. A. ^{[3
]}

Kusnetsova, V. A. ^{[3
]}

Sorotsky, D. V. ^{[3
]}

Solov'eva, O. A. ^{[3
]}

Spasov, A. A. ^{[3
]}

机构：

[1] Moscow MV Lomonosov State Univ, 1 Bldg 3 Leninskie Gory, Moscow 119991, Russia

[2] Russian Acad Sci, Inst Physiocologically Act Cpds, Chernogolovka 142432, Moscow Region, Russia

[3] Volgograd State Univ, Volgograd 400131, Russia

来源：

RUSSIAN CHEMICAL BULLETIN | 2015年 / 64卷 / 09期

基金：

俄罗斯基础研究基金会;

关键词：

2,6-di-tert-butylphenol; ferrocene; lipid peroxidation; antioxidant activity; protein glycation; MAILLARD REACTION; END-PRODUCTS; ANTIOXIDANT ACTIVITY; COMPLICATIONS; MECHANISMS; OXIDATION; DISEASES; SYSTEM;

D O I：

10.1007/s11172-015-1138-5

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Antioxidant and antiglycating activities of 2,6-di-tert-butyl-4-[N-(4-pyridyl) imino-methyl] phenol (1), 2,6-di-tert-butyl-4-[N-(3-pyridylmethyl)-iminomethyl] phenol (2) and N-(3,5-di-tert-butyl-4-hydroxyphenyl)iminomethylferrocene (3) have been studied. Antioxidant activity of 2,6-di-tert-butylphenol bearing ferrocenyl moiety was shown to be sufficiently higher than that of the compounds 1 and 2. Based on the data obtained in comparison with aminoguanidine which is an effective protein glycation inhibitor it was established that the introduction of ferrocenyl moiety into 2,6-di-tert-butylphenol results in a dramatic increase in the antiglycating activity exceeding that for aminoguanidine.

引用

页码：2195 / 2202

页数：8

共 50 条

[31] Recent advances on ferrocene-based photoinitiating systems
Dumur, Frederic
EUROPEAN POLYMER JOURNAL, 2021, 147 (147)
[32] Toward ferrocene-based molecular-transistors.
Engtrakul, C
Sita, LR
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2000, 220 : U519 - U519
[33] Ferrocene-based ureas as multisignaling receptors for anions
Oton, Francisco
Tarraga, Alberto
Espinosa, Arturo
Velasco, Maria D.
Molina, Pedro
JOURNAL OF ORGANIC CHEMISTRY, 2006, 71 (12): : 4590 - 4598
[34] Full-conjugated ferrocene-based polymers
Shi Jianbing
Zhi Junge
Bin, Tong
Wei, Zhao
Shen Jinbo
Dong Yuping
PROGRESS IN CHEMISTRY, 2008, 20 (04) : 558 - 564
[35] Ferrocene-based bidentate Lewis-acids.
Jäkle, F
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2001, 221 : U691 - U691
[36] Miscellaneous applications of ferrocene-based peptides/amides
Lal, Bhajan
Badshah, Amin
Altaf, Ataf Ali
Khan, Nasir
Ullah, Shafiq
APPLIED ORGANOMETALLIC CHEMISTRY, 2011, 25 (12) : 843 - 855
[37] Electrochemical Applications of Ferrocene-Based Coordination Polymers
Hu, Mao-Lin
Abbasi-Azad, Mahsa
Habibi, Behnam
Rouhani, Farzaneh
Moghanni-Bavil-Olyaei, Hamed
Liu, Kuan-Guan
Morsali, Ali
CHEMPLUSCHEM, 2020, 85 (11): : 2397 - 2418
[38] Synthesis of Soluble Ferrocene-Based Polythiophenes and Their Properties
Hamad Khalid
Li Wang
Haojie Yu
Muhammad Akram
Nasir M. Abbasi
Ruoli Sun
Muhammad Saleem
Yongsheng Zain-ul-Abdin
Journal of Inorganic and Organometallic Polymers and Materials, 2015, 25 : 1511 - 1520
[39] Synthesis of Soluble Ferrocene-Based Polythiophenes and Their Properties
Khalid, Hamad
Wang, Li
Yu, Haojie
Akram, Muhammad
Abbasi, Nasir M.
Sun, Ruoli
Saleem, Muhammad
Zain-ul-Abdin
Chen, Yongsheng
JOURNAL OF INORGANIC AND ORGANOMETALLIC POLYMERS AND MATERIALS, 2015, 25 (06) : 1511 - 1520
[40] FERROCENE-BASED LIQUID-CRYSTALLINE COMPOUNDS
SINGH, P
RAUSCH, MD
LENZ, RW
LIQUID CRYSTALS, 1991, 9 (01) : 19 - 26

← 1 2 3 4 5 →