Cassava is an important and useful plant in supporting industrial activities. Therefore, understanding supply chain and profitability can be a basis provision for raw materials and increasing farmer's income. This study aims to: (1) know the supply chain of cassava production and the influencing factors, (2) to know the profitability of cassava in integrated farming. The study was conducted in Kabupaten Trenggalek, East Java during the planting season of 2012. The results showed (1) the supply of cassava production 2007-2012 decreased with an average of 4.5% per year. Key contributions are productivity growth of 3.7% and shrinkage of 3.4%. (2) The profitability of cassava that integrates with goat cattle is 2.03, while those of that are not integrated are 2.02. Total household income of farmers integration Rp 1.460.125, - higher than unintegrated Rp 981.530, - In the long run, there is an increase of animal feed, soil fertility improvement, environmental preservation and outpouring work for farmers' family members.