Crystallization and preliminary crystallographic studies of an apoptosis-linked calcium-binding protein ALG-2

被引:3
作者
Fang, WA
Zhang, MJ
Gong, W [1 ]
机构
[1] Univ Sci & Technol China, Struct Biol Lab, Anhua 230026, Peoples R China
[2] Univ Sci & Technol China, Sch Life Sci, Anhua 230026, Peoples R China
[3] Hong Kong Univ Sci & Technol, Dept Biochem, Hong Kong, Hong Kong, Peoples R China
来源
ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY | 2001年 / 57卷
关键词
D O I
10.1107/S090744490100926X
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
ALG-2 is an apoptosis-linked Ca2+-binding protein. It is required for T-cell receptor-induced, Fas-induced and glucocorticoid-induced cell death. Structurally, ALG-2 contains five putative EF-hand Ca2+-binding sites. Ca2+-free ALG-2 was crystallized in two crystal forms by the hanging-drop vapour-diffusion method.
引用
收藏
页码:1162 / 1163
页数:2
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