Incidence and Prevalence of Unrecognized Myocardial Infarction in People With Diabetes

被引:27
作者
MacDonald, Michael R. [1 ]
Petrie, Mark C. [1 ]
Home, Philip D. [2 ,3 ]
Komajda, Michel [4 ,5 ]
Jones, Nigel P. [6 ]
Beck-Nielsen, Henning [7 ]
Gomis, Ramon [8 ]
Hanefeld, Markolf [9 ]
Pocock, Stuart J. [10 ]
Curtis, Paula S. [11 ]
McMurray, John J. V. [12 ]
机构
[1] Golden Jubilee Natl Hosp, Glasgow, Lanark, Scotland
[2] Newcastle Diabet Ctr, Newcastle Upon Tyne, Tyne & Wear, England
[3] Newcastle Univ, Newcastle Upon Tyne NE1 7RU, Tyne & Wear, England
[4] Univ Paris 06, Paris, France
[5] Hop La Pitie Salpetriere, Dept Cardiol, Paris, France
[6] GlaxoSmithKline Res & Dev Ltd, Harlow, Essex, England
[7] Dept Endocrinol & Metab, Odense, Denmark
[8] Univ Barcelona, Hosp Clin Idibaps Ciberdem, Barcelona, Spain
[9] Forsch Bereich Endokrinol & Stoffwechsel, Zentrum Klin Studien, Dresden, Germany
[10] London Sch Hyg & Trop Med, Med Stat Unit, London WC1, England
[11] GlaxoSmithKline Res & Dev Ltd, Greenford, Middx, England
[12] Univ Glasgow, Cardiovasc Res Ctr, British Heart Fdn, Glasgow, Lanark, Scotland
关键词
PROGNOSIS; REYKJAVIK;
D O I
10.2337/dc10-2398
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
OBJECTIVE-To examine the prevalence and incidence of unrecognized myocardial infarction in a contemporary population with type 2 diabetes. RESEARCH DESIGN AND METHODS-We performed a retrospective analysis of the electrocardiograms (ECGs) recorded at baseline and after 2 years for the first 1,004 type 2 diabetic individuals to be randomized in the Rosiglitazone Evaluated for Cardiac Outcomes and Regulation of Glycemia in Diabetes (RECORD) study. RESULTS-ECGs suitable for analysis were obtained from 669 participants. The prevalence of unrecognized Q-wave myocardial infarction at baseline was 1.9% (n = 13). The incidence of unrecognized Q-wave myocardial infarction at the end of 2 years of follow-up was 1.5/1,000-person-years (n = 2). One-third (13 of 39) of prevalent and one-quarter (2 of 8) of incident myocardial infarctions were unrecognized. CONCLUSIONS-Although the prevalence and incidence of myocardial infarction was low, unrecognized Q-wave myocardial infarctions made up a substantial proportion of all events.
引用
收藏
页码:1394 / 1396
页数:3
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