Incidence and Prevalence of Unrecognized Myocardial Infarction in People With Diabetes

被引：29

作者：

MacDonald, Michael R. ^{[1
]}

Petrie, Mark C. ^{[1
]}

Home, Philip D. ^{[2
,3
]}

Komajda, Michel ^{[4
,5
]}

Jones, Nigel P. ^{[6
]}

Beck-Nielsen, Henning ^{[7
]}

Gomis, Ramon ^{[8
]}

Hanefeld, Markolf ^{[9
]}

Pocock, Stuart J. ^{[10
]}

Curtis, Paula S. ^{[11
]}

McMurray, John J. V. ^{[12
]}

机构：

[1] Golden Jubilee Natl Hosp, Glasgow, Lanark, Scotland

[2] Newcastle Diabet Ctr, Newcastle Upon Tyne, Tyne & Wear, England

[3] Newcastle Univ, Newcastle Upon Tyne NE1 7RU, Tyne & Wear, England

[4] Univ Paris 06, Paris, France

[5] Hop La Pitie Salpetriere, Dept Cardiol, Paris, France

[6] GlaxoSmithKline Res & Dev Ltd, Harlow, Essex, England

[7] Dept Endocrinol & Metab, Odense, Denmark

[8] Univ Barcelona, Hosp Clin Idibaps Ciberdem, Barcelona, Spain

[9] Forsch Bereich Endokrinol & Stoffwechsel, Zentrum Klin Studien, Dresden, Germany

[10] London Sch Hyg & Trop Med, Med Stat Unit, London WC1, England

[11] GlaxoSmithKline Res & Dev Ltd, Greenford, Middx, England

[12] Univ Glasgow, Cardiovasc Res Ctr, British Heart Fdn, Glasgow, Lanark, Scotland

来源：

DIABETES CARE | 2011年 / 34卷 / 06期

关键词：

PROGNOSIS; REYKJAVIK;

D O I：

10.2337/dc10-2398

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

OBJECTIVE-To examine the prevalence and incidence of unrecognized myocardial infarction in a contemporary population with type 2 diabetes. RESEARCH DESIGN AND METHODS-We performed a retrospective analysis of the electrocardiograms (ECGs) recorded at baseline and after 2 years for the first 1,004 type 2 diabetic individuals to be randomized in the Rosiglitazone Evaluated for Cardiac Outcomes and Regulation of Glycemia in Diabetes (RECORD) study. RESULTS-ECGs suitable for analysis were obtained from 669 participants. The prevalence of unrecognized Q-wave myocardial infarction at baseline was 1.9% (n = 13). The incidence of unrecognized Q-wave myocardial infarction at the end of 2 years of follow-up was 1.5/1,000-person-years (n = 2). One-third (13 of 39) of prevalent and one-quarter (2 of 8) of incident myocardial infarctions were unrecognized. CONCLUSIONS-Although the prevalence and incidence of myocardial infarction was low, unrecognized Q-wave myocardial infarctions made up a substantial proportion of all events.

引用

页码：1394 / 1396

页数：3

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