Effective membrane model of the immunological synapse

被引：39

作者：

Raychaudhuri, S ^{[1
]}

Chakraborty, AK

Kardar, M

机构：

[1] Univ Calif Berkeley, Dept Chem Engn, Berkeley, CA 94720 USA

[2] Univ Calif Berkeley, Dept Chem, Berkeley, CA 94720 USA

[3] Univ Calif Berkeley, Lawrence Berkeley Lab, Div Mat Sci, Berkeley, CA 94720 USA

[4] Univ Calif Berkeley, Lawrence Berkeley Lab, Phys Biosci Div, Berkeley, CA 94720 USA

[5] MIT, Dept Phys, Cambridge, MA 02139 USA

来源：

PHYSICAL REVIEW LETTERS | 2003年 / 91卷 / 20期

基金：

美国国家科学基金会; 美国国家卫生研究院;

关键词：

D O I：

10.1103/PhysRevLett.91.208101

中图分类号：

O4 [物理学];

学科分类号：

0702 ;

摘要：

The immunological synapse is a patterned collection of different types of receptors and ligands that forms in the intercellular junction between T cells and antigen presenting cells during recognition. The synapse is implicated in information transfer between cells, and is characterized by different spatial patterns of receptors at different stages in the life cycle of T cells. We obtain a minimalist model that captures this experimentally observed phenomenology. A functional renormalization group analysis provides further insights.

引用

页数：4

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