Immunohistochemical analysis of a dentinogenic ghost cell tumour

被引：14

作者：

Piattelli, A

Fioroni, M

Di Alberti, L

Rubini, C

机构：

[1] Univ G dAnnunzio, Sch Dent, Chieti, Italy

[2] UCL Eastman Dent Inst Oral Hlth Care Sci, Dept Oral Med, London, England

[3] Univ Ancona, Sch Dent, Ancona, Italy

[4] Univ Ancona, Dept Pathol, Ancona, Italy

来源：

ORAL ONCOLOGY | 1998年 / 34卷 / 06期

关键词：

apoptosis; bcl-2; calcifying odontogenic cyst; cytokeratins; dentinogenic ghost cell tumour; p53;

D O I：

10.1016/S1368-8375(98)00034-7

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

A dentinogenic ghost cell tumour in an 80-year-old male patient is presented. It is an extremely rare tumour and only 10 cases have been reported in the English literature. The lesion showed odontogenic epithelium, ghost cells, dentinoid, giant cells. The immunohistochemical analysis for Mib-1 and bcl-2 showed a strong positivity of the cells of the odontogenic epithelium, while with p53 only a rare positivity was observed. Completely negative were the ghost cells, giant cells and dentinoid material. In this tumour the cells expressing Mib-1 and bcl-2 could be the cells that proliferate, and that could undergo malignant transformation. (C) 1998 Elsevier Science Ltd. All rights reserved.

引用

页码：502 / 507

页数：6