Pseudopyronines A and B, α-pyrones produced by a marine Pseudomonas sp F92S91, and evidence for the conversion of 4-hydroxy-α-pyrone to 3-furanone

被引：36

作者：

Kong, FM ^{[1
]}

Singh, MP ^{[1
]}

Carter, GT ^{[1
]}

机构：

[1] Wyeth Res, Pearl River, NY 10965 USA

来源：

JOURNAL OF NATURAL PRODUCTS | 2005年 / 68卷 / 06期

关键词：

D O I：

10.1021/np050038v

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

In our search for inhibitors of bacterial fatty acid biosynthesis, two new alpha-pyrones, pseudopyronines A (1) and B (2), were isolated from a marine Pseudomonas sp. F92S91. The naturally occurring a-pyrones appeared to be unstable, evidenced by the conversion of pseudopyronine B into an oxidation product, 3-furanone (3). Structural elucidations were made by spectroscopic analyses including 2D-NMR data.

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页码：920 / 923

页数：4

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