Acivicin induce filamentous growth of Saccharomyces cerevisiae

被引:2
|
作者
Miyake, T
Sammoto, H
Ono, B
机构
[1] Ind Technol Ctr, Okayama 7011296, Japan
[2] Ritsumeikan Univ, Fac Sci & Engn, Dept Biotechnol, Shiga 5258577, Japan
关键词
yeast; acivicin; filamentous growth; industrial strain;
D O I
10.1271/bbb.67.2283
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The antibiotic acivicin is a known inhibitor of gamma-glutamyl transpeptidase (gammaGTP). We found that acivicin can induce filamentous growth in both diploid and haploid cells of Saccharomyces cerevisiae. This phenomenon is not related to the inhibition of gammaGTP or interference in glutathione metabolism. Interestingly, yeasts used in the brewing industry are more sensitive to acivicin, suggesting that this dimorphological differentiation may be related to some characteristics of these particular strains.
引用
收藏
页码:2283 / 2285
页数:3
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