RNA-sequencing analysis of core binding factor AML identifies recurrent ZBTB7A mutations and defines RUNX1-CBFA2T3 fusion signature

被引:52
作者
Lavallee, Vincent-Philippe [1 ,2 ]
Lemieux, Sebastien [1 ,3 ]
Boucher, Genevieve [1 ]
Gendron, Patrick [1 ]
Boivin, Isabel [1 ]
Armstrong, Richard N. [1 ]
Sauvageau, Guy [1 ,2 ,4 ,5 ]
Hebert, Josee [1 ,2 ,4 ,5 ]
机构
[1] Univ Montreal, Leucegene Project, Inst Res Immunol & Canc, Montreal, PQ, Canada
[2] Hop Maison Neuve Rosemont, Div Hematol, Montreal, PQ H1T 2M4, Canada
[3] Univ Montreal, Dept Comp Sci & Operat Res, Montreal, PQ, Canada
[4] Hop Maison Neuve Rosemont, Quebec Leukemia Cell Bank, Montreal, PQ H1T 2M4, Canada
[5] Univ Montreal, Dept Med, Fac Med, Montreal, PQ H3C 3J7, Canada
关键词
ACUTE MYELOID-LEUKEMIA; GENE; LANDSCAPE; CANCER; KIT;
D O I
10.1182/blood-2016-03-703868
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
引用
收藏
页码:2498 / 2501
页数:4
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